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Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review

This review delves into the utilization of intermetallic alloys (IMAs) as advanced biomaterials for medical implants, scrutinizing their conceptual framework, fabrication challenges, and diverse manufacturing techniques such as casting, powder metallurgy, and additive manufacturing. Manufacturing te...

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Main Authors: Nasiri-Tabrizi, Bahman, Basirun, Wan Jefrey, Walvekar, Rashmi, Yeong, Chai Hong, Phang, Siew Wei
Format: Article
Published: Elsevier 2024
Subjects:
QD Chemistry
TP Chemical technology
Online Access:http://eprints.um.edu.my/45136/
https://doi.org/10.1016/j.bioadv.2024.213854
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spelling my.um.eprints.451362024-09-19T01:45:31Z http://eprints.um.edu.my/45136/ Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review Nasiri-Tabrizi, Bahman Basirun, Wan Jefrey Walvekar, Rashmi Yeong, Chai Hong Phang, Siew Wei QD Chemistry TP Chemical technology This review delves into the utilization of intermetallic alloys (IMAs) as advanced biomaterials for medical implants, scrutinizing their conceptual framework, fabrication challenges, and diverse manufacturing techniques such as casting, powder metallurgy, and additive manufacturing. Manufacturing techniques such as casting, powder metallurgy, additive manufacturing, and injection molding are discussed, with specific emphasis on achieving optimal grain sizes, surface roughness, and mechanical properties. Post-treatment methods aimed at refining surface quality, dimensional precision, and mechanical properties of IMAs are explored, including the use of heat treatments to enhance biocompatibility and corrosion resistance. The review presents an in-depth examination of IMAs-based implantable biomaterials, covering lab-scale developments and commercial-scale implants. Specific IMAs such as Nickel Titanium, Titanium Aluminides, Iron Aluminides, Magnesium-based IMAs, Zirconium-based IMAs, and High-entropy alloys (HEAs) are highlighted, with detailed discussions on their mechanical properties, including strength, elastic modulus, and corrosion resistance. Future directions are outlined, with an emphasis on the anticipated growth in the orthopedic devices market and the role of IMAs in meeting this demand. The potential of porous IMAs in orthopedics is explored, with emphasis on achieving optimal pore sizes and distributions for enhanced osseointegration. The review concludes by highlighting the ongoing need for research and development efforts in IMAs technologies, including advancements in design and fabrication techniques. Elsevier 2024-07 Article PeerReviewed Nasiri-Tabrizi, Bahman and Basirun, Wan Jefrey and Walvekar, Rashmi and Yeong, Chai Hong and Phang, Siew Wei (2024) Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review. Biomaterials Advances, 161. p. 213854. ISSN 2772-9508, DOI https://doi.org/10.1016/j.bioadv.2024.213854 <https://doi.org/10.1016/j.bioadv.2024.213854>. https://doi.org/10.1016/j.bioadv.2024.213854 10.1016/j.bioadv.2024.213854
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic QD Chemistry
TP Chemical technology
spellingShingle QD Chemistry
TP Chemical technology
Nasiri-Tabrizi, Bahman
Basirun, Wan Jefrey
Walvekar, Rashmi
Yeong, Chai Hong
Phang, Siew Wei
Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
description This review delves into the utilization of intermetallic alloys (IMAs) as advanced biomaterials for medical implants, scrutinizing their conceptual framework, fabrication challenges, and diverse manufacturing techniques such as casting, powder metallurgy, and additive manufacturing. Manufacturing techniques such as casting, powder metallurgy, additive manufacturing, and injection molding are discussed, with specific emphasis on achieving optimal grain sizes, surface roughness, and mechanical properties. Post-treatment methods aimed at refining surface quality, dimensional precision, and mechanical properties of IMAs are explored, including the use of heat treatments to enhance biocompatibility and corrosion resistance. The review presents an in-depth examination of IMAs-based implantable biomaterials, covering lab-scale developments and commercial-scale implants. Specific IMAs such as Nickel Titanium, Titanium Aluminides, Iron Aluminides, Magnesium-based IMAs, Zirconium-based IMAs, and High-entropy alloys (HEAs) are highlighted, with detailed discussions on their mechanical properties, including strength, elastic modulus, and corrosion resistance. Future directions are outlined, with an emphasis on the anticipated growth in the orthopedic devices market and the role of IMAs in meeting this demand. The potential of porous IMAs in orthopedics is explored, with emphasis on achieving optimal pore sizes and distributions for enhanced osseointegration. The review concludes by highlighting the ongoing need for research and development efforts in IMAs technologies, including advancements in design and fabrication techniques.
format Article
author Nasiri-Tabrizi, Bahman
Basirun, Wan Jefrey
Walvekar, Rashmi
Yeong, Chai Hong
Phang, Siew Wei
author_facet Nasiri-Tabrizi, Bahman
Basirun, Wan Jefrey
Walvekar, Rashmi
Yeong, Chai Hong
Phang, Siew Wei
author_sort Nasiri-Tabrizi, Bahman
title Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
title_short Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
title_full Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
title_fullStr Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
title_full_unstemmed Exploring the potential of intermetallic alloys as implantable biomaterials: A comprehensive review
title_sort exploring the potential of intermetallic alloys as implantable biomaterials: a comprehensive review
publisher Elsevier
publishDate 2024
url http://eprints.um.edu.my/45136/
https://doi.org/10.1016/j.bioadv.2024.213854
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score 13.211869

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