Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia

E-cigarette has been marketed over years as one of alternative smoking cessation aid offered for consumer worldwide. The addition of flavouring in e-liquid has become a major factor that contributes to the appeal of using e-cigarette among a non-smoker and youngster has raised concerns due to possib...

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Main Authors: Hashim, Syaza Ahmad, Shameli, Kamyar, Md Akhir, Fazreena Nadia, Salleh, Madihah Md, Ismail, Norliana, Hassan, Noraryana, Hara, Hirofumi, Mohamad, Edzrol Niza, Mohamad, Shaza Eva
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Published: Penerbit Akademia Baru 2022
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Online Access:http://eprints.um.edu.my/43966/
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spelling my.um.eprints.439662023-11-30T08:16:27Z http://eprints.um.edu.my/43966/ Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia Hashim, Syaza Ahmad Shameli, Kamyar Md Akhir, Fazreena Nadia Salleh, Madihah Md Ismail, Norliana Hassan, Noraryana Hara, Hirofumi Mohamad, Edzrol Niza Mohamad, Shaza Eva TP Chemical technology E-cigarette has been marketed over years as one of alternative smoking cessation aid offered for consumer worldwide. The addition of flavouring in e-liquid has become a major factor that contributes to the appeal of using e-cigarette among a non-smoker and youngster has raised concerns due to possible risk and hazard outcomes in daily usage is remain unclear to date. In order to fully understand the e-cigarette attributes towards human health and environment; 17 e-liquid products locally sold were bought and analysed by gas chromatography-mass spectrometer (GC-MS) in order to determine the chemical constituent of e-liquid, especially the flavouring additive. A total of 19 out of 41 identified chemical compounds were detected as a new flavouring agent used i n e-liquid products since there was no previous report on this. Many of the flavour chemicals possessed a risk of inhalation toxicity because they were classified as corrosive and/or irritant, with only a few having acute toxicity and the potential to cause cancer. Moreover, several chemical compounds to be concerned such as stimulant as well as opioid types were unexpectedly identified in the e-liquid. Thus, this finding indicate that the chemical constituent of e-liquid contained unknown risk of toxicity and further research is needed to fully understand the possibility of adverse effect in using e-cigarette. © 2022, Penerbit Akademia Baru. All rights reserved. Penerbit Akademia Baru 2022 Article PeerReviewed Hashim, Syaza Ahmad and Shameli, Kamyar and Md Akhir, Fazreena Nadia and Salleh, Madihah Md and Ismail, Norliana and Hassan, Noraryana and Hara, Hirofumi and Mohamad, Edzrol Niza and Mohamad, Shaza Eva (2022) Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia. Journal of Advanced Research in Applied Sciences and Engineering Technology, 26 (1). 15 -22. ISSN 24621943, DOI https://doi.org/10.37934/araset.26.1.1522 <https://doi.org/10.37934/araset.26.1.1522>. 10.37934/araset.26.1.1522
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Hashim, Syaza Ahmad
Shameli, Kamyar
Md Akhir, Fazreena Nadia
Salleh, Madihah Md
Ismail, Norliana
Hassan, Noraryana
Hara, Hirofumi
Mohamad, Edzrol Niza
Mohamad, Shaza Eva
Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
description E-cigarette has been marketed over years as one of alternative smoking cessation aid offered for consumer worldwide. The addition of flavouring in e-liquid has become a major factor that contributes to the appeal of using e-cigarette among a non-smoker and youngster has raised concerns due to possible risk and hazard outcomes in daily usage is remain unclear to date. In order to fully understand the e-cigarette attributes towards human health and environment; 17 e-liquid products locally sold were bought and analysed by gas chromatography-mass spectrometer (GC-MS) in order to determine the chemical constituent of e-liquid, especially the flavouring additive. A total of 19 out of 41 identified chemical compounds were detected as a new flavouring agent used i n e-liquid products since there was no previous report on this. Many of the flavour chemicals possessed a risk of inhalation toxicity because they were classified as corrosive and/or irritant, with only a few having acute toxicity and the potential to cause cancer. Moreover, several chemical compounds to be concerned such as stimulant as well as opioid types were unexpectedly identified in the e-liquid. Thus, this finding indicate that the chemical constituent of e-liquid contained unknown risk of toxicity and further research is needed to fully understand the possibility of adverse effect in using e-cigarette. © 2022, Penerbit Akademia Baru. All rights reserved.
format Article
author Hashim, Syaza Ahmad
Shameli, Kamyar
Md Akhir, Fazreena Nadia
Salleh, Madihah Md
Ismail, Norliana
Hassan, Noraryana
Hara, Hirofumi
Mohamad, Edzrol Niza
Mohamad, Shaza Eva
author_facet Hashim, Syaza Ahmad
Shameli, Kamyar
Md Akhir, Fazreena Nadia
Salleh, Madihah Md
Ismail, Norliana
Hassan, Noraryana
Hara, Hirofumi
Mohamad, Edzrol Niza
Mohamad, Shaza Eva
author_sort Hashim, Syaza Ahmad
title Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
title_short Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
title_full Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
title_fullStr Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
title_full_unstemmed Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia
title_sort identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in malaysia
publisher Penerbit Akademia Baru
publishDate 2022
url http://eprints.um.edu.my/43966/
_version_ 1784511889176264704
score 13.211869