Staff View: Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial

Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial

Background and Aims: Postoperative sore throat (POST) is an undesirable event reported in up to 62 of patients receiving general anaesthesia (GA). The incidence of POST following GA using a supraglottic airway device (SAD) is approximately 50, with symptoms persisting up to 48 h. We examined the rol...

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Main Authors:	Sundaraj, Sebastian, Shariffuddin, Ina Ismiarti, Chaw, Sook Hui, Wan Zakaria, Wan, Shan Ng, Kevin, Ruslan, Shairil
Format:	Article
Published:	Medknow Publications 2022
Subjects:	R Medicine RA0421 Public health. Hygiene. Preventive Medicine
Online Access:	http://eprints.um.edu.my/43782/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135489930&doi=10.4103%2fija.ija_809_21&partnerID=40&md5=4e78a47cc896c814772509835ee3e12f
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spelling	my.um.eprints.437822024-11-14T07:19:33Z http://eprints.um.edu.my/43782/ Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial Sundaraj, Sebastian Shariffuddin, Ina Ismiarti Chaw, Sook Hui Wan Zakaria, Wan Shan Ng, Kevin Ruslan, Shairil R Medicine RA0421 Public health. Hygiene. Preventive Medicine Background and Aims: Postoperative sore throat (POST) is an undesirable event reported in up to 62 of patients receiving general anaesthesia (GA). The incidence of POST following GA using a supraglottic airway device (SAD) is approximately 50, with symptoms persisting up to 48 h. We examined the role of preoperative lozenges containing amylmetacresol and dichlorobenzyl alcohol (AMC/DCBA) with lignocaine (Strepsils ® Max Plus) in reducing the incidence and intensity of POST following GA using SAD. Methods: We conducted a prospective, double-blinded, randomised, placebo-controlled trial involving 88 adults receiving GA for elective surgery using SAD not exceeding 2 h. Patients received either Strepsils Max Plus (Strepsils-LA group) or a placebo before induction of GA. The incidence and intensity of sore throat, dysphagia and dysphonia was measured using the Verbal Rating Scale at 30 min (early) and at 24 h (late) after removal of SAD. Results: Overall POST incidence was lower in the Strepsils-LA group (27.7 ver Medknow Publications 2022 Article PeerReviewed Sundaraj, Sebastian and Shariffuddin, Ina Ismiarti and Chaw, Sook Hui and Wan Zakaria, Wan and Shan Ng, Kevin and Ruslan, Shairil (2022) Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial. Indian Journal of Anaesthesia, 66 (7). 523 – 529. ISSN 0019-5049, DOI https://doi.org/10.4103/ija.ija_809_21 <https://doi.org/10.4103/ija.ija_809_21>. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135489930&doi=10.4103%2fija.ija_809_21&partnerID=40&md5=4e78a47cc896c814772509835ee3e12f 10.4103/ija.ija_809_21
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	R Medicine RA0421 Public health. Hygiene. Preventive Medicine
spellingShingle	R Medicine RA0421 Public health. Hygiene. Preventive Medicine Sundaraj, Sebastian Shariffuddin, Ina Ismiarti Chaw, Sook Hui Wan Zakaria, Wan Shan Ng, Kevin Ruslan, Shairil Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
description	Background and Aims: Postoperative sore throat (POST) is an undesirable event reported in up to 62 of patients receiving general anaesthesia (GA). The incidence of POST following GA using a supraglottic airway device (SAD) is approximately 50, with symptoms persisting up to 48 h. We examined the role of preoperative lozenges containing amylmetacresol and dichlorobenzyl alcohol (AMC/DCBA) with lignocaine (Strepsils ® Max Plus) in reducing the incidence and intensity of POST following GA using SAD. Methods: We conducted a prospective, double-blinded, randomised, placebo-controlled trial involving 88 adults receiving GA for elective surgery using SAD not exceeding 2 h. Patients received either Strepsils Max Plus (Strepsils-LA group) or a placebo before induction of GA. The incidence and intensity of sore throat, dysphagia and dysphonia was measured using the Verbal Rating Scale at 30 min (early) and at 24 h (late) after removal of SAD. Results: Overall POST incidence was lower in the Strepsils-LA group (27.7 ver
format	Article
author	Sundaraj, Sebastian Shariffuddin, Ina Ismiarti Chaw, Sook Hui Wan Zakaria, Wan Shan Ng, Kevin Ruslan, Shairil
author_facet	Sundaraj, Sebastian Shariffuddin, Ina Ismiarti Chaw, Sook Hui Wan Zakaria, Wan Shan Ng, Kevin Ruslan, Shairil
author_sort	Sundaraj, Sebastian
title	Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
title_short	Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
title_full	Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
title_fullStr	Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
title_full_unstemmed	Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial
title_sort	preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: a double-blinded, randomised, placebo-controlled trial
publisher	Medknow Publications
publishDate	2022
url	http://eprints.um.edu.my/43782/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135489930&doi=10.4103%2fija.ija_809_21&partnerID=40&md5=4e78a47cc896c814772509835ee3e12f
_version_	1816130416143237120
score	13.244413

Preoperative amylmetacresol and dichlorobenzyl alcohol with lignocaine lozenge reduces postoperative sore throat following general anaesthesia using supraglottic airway devices: A double-blinded, randomised, placebo-controlled trial

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