Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients

This work investigated the demonstration of acetone detection device as a potential tool to diagnose diabetes patients. It offers simple and low cost approach based on glass substrate platform. The glass substrate was coated with agarose gel as a sensitive material to increase the sensing response....

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Main Authors: Jali, Mohd Hafiz, Zamzuri, Ahmad Nur Azeim Ahmad, Rahim, Hazli Rafis Abdul, Johari, Md. Ashadi Md, Ahmad, Aminah, Baharom, Mohamad Faizal, Zain, Huda Adnan, Harun, Sulaiman Wadi
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Published: Przeglad Elektrotechniczny 2022
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Online Access:http://eprints.um.edu.my/43523/
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spelling my.um.eprints.435232023-10-20T07:32:57Z http://eprints.um.edu.my/43523/ Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients Jali, Mohd Hafiz Zamzuri, Ahmad Nur Azeim Ahmad Rahim, Hazli Rafis Abdul Johari, Md. Ashadi Md Ahmad, Aminah Baharom, Mohamad Faizal Zain, Huda Adnan Harun, Sulaiman Wadi TA Engineering (General). Civil engineering (General) TK Electrical engineering. Electronics Nuclear engineering This work investigated the demonstration of acetone detection device as a potential tool to diagnose diabetes patients. It offers simple and low cost approach based on glass substrate platform. The glass substrate was coated with agarose gel as a sensitive material to increase the sensing response. It has superiority in term of high porosity and capable to absorb molecule around it. The sensing mechanism is based on the change in refractive index (RI) of the agarose gel coating layer when exposed to variation acetone concentration level. This is due to the intensity of the light weakening by absorption and scattering when light propagated through the sensing material. The proposed sensor produces a significant response towards acetone concentrations with the output voltage reduced linearly from 1.6V to 1.2V. The sensitivity and resolution of the agarose coated glass substrate improves by a factor of 1.08 and 1.14 respectively as compared to uncoated glass substrate. It also performed better in term of linearity, stability, response time and hysteresis. The non-involvement of costly laser source based instruments make the proposed sensor become more practical for large production while maintaining a good sensing performances. Based on the experiment results, the proposed acetone sensor has a persuasive potential as an early biomarker for diabetes diagnosis tool. © 2022 Wydawnictwo SIGMA-NOT. All rights reserved. Przeglad Elektrotechniczny 2022 Article PeerReviewed Jali, Mohd Hafiz and Zamzuri, Ahmad Nur Azeim Ahmad and Rahim, Hazli Rafis Abdul and Johari, Md. Ashadi Md and Ahmad, Aminah and Baharom, Mohamad Faizal and Zain, Huda Adnan and Harun, Sulaiman Wadi (2022) Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients. Przeglad Elektrotechniczny, 98 (5). 71 – 75. ISSN 0033-2097, DOI https://doi.org/10.15199/48.2022.05.13 <https://doi.org/10.15199/48.2022.05.13>. 10.15199/48.2022.05.13
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic TA Engineering (General). Civil engineering (General)
TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TA Engineering (General). Civil engineering (General)
TK Electrical engineering. Electronics Nuclear engineering
Jali, Mohd Hafiz
Zamzuri, Ahmad Nur Azeim Ahmad
Rahim, Hazli Rafis Abdul
Johari, Md. Ashadi Md
Ahmad, Aminah
Baharom, Mohamad Faizal
Zain, Huda Adnan
Harun, Sulaiman Wadi
Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
description This work investigated the demonstration of acetone detection device as a potential tool to diagnose diabetes patients. It offers simple and low cost approach based on glass substrate platform. The glass substrate was coated with agarose gel as a sensitive material to increase the sensing response. It has superiority in term of high porosity and capable to absorb molecule around it. The sensing mechanism is based on the change in refractive index (RI) of the agarose gel coating layer when exposed to variation acetone concentration level. This is due to the intensity of the light weakening by absorption and scattering when light propagated through the sensing material. The proposed sensor produces a significant response towards acetone concentrations with the output voltage reduced linearly from 1.6V to 1.2V. The sensitivity and resolution of the agarose coated glass substrate improves by a factor of 1.08 and 1.14 respectively as compared to uncoated glass substrate. It also performed better in term of linearity, stability, response time and hysteresis. The non-involvement of costly laser source based instruments make the proposed sensor become more practical for large production while maintaining a good sensing performances. Based on the experiment results, the proposed acetone sensor has a persuasive potential as an early biomarker for diabetes diagnosis tool. © 2022 Wydawnictwo SIGMA-NOT. All rights reserved.
format Article
author Jali, Mohd Hafiz
Zamzuri, Ahmad Nur Azeim Ahmad
Rahim, Hazli Rafis Abdul
Johari, Md. Ashadi Md
Ahmad, Aminah
Baharom, Mohamad Faizal
Zain, Huda Adnan
Harun, Sulaiman Wadi
author_facet Jali, Mohd Hafiz
Zamzuri, Ahmad Nur Azeim Ahmad
Rahim, Hazli Rafis Abdul
Johari, Md. Ashadi Md
Ahmad, Aminah
Baharom, Mohamad Faizal
Zain, Huda Adnan
Harun, Sulaiman Wadi
author_sort Jali, Mohd Hafiz
title Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
title_short Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
title_full Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
title_fullStr Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
title_full_unstemmed Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
title_sort detection of acetone as a potential non-invasive diagnosis tool for diabetes patients
publisher Przeglad Elektrotechniczny
publishDate 2022
url http://eprints.um.edu.my/43523/
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score 13.211869