Staff View: In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants

In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants

The commonly used metallic biomaterials fail to prove durability for orthopedics due to their lack of biocompatibility and poor bioactivity which weakens the bonding to bones. Metallic glasses (MGs) have attracted attention as an alternative biomaterial for orthopedics owing to their superior mechan...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ibrahim, Mahmoud Z., Halilu, Ahmed, Sarhan, Ahmed A. D., Kuo, T. Y., Yusuf, Farazila, Shaikh, M. O., Hamdi, M.
Format:	Article
Published:	Elsevier 2022
Subjects:	TA Engineering (General). Civil engineering (General)
Online Access:	http://eprints.um.edu.my/43011/
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.um.eprints.43011
record_format	eprints
spelling	my.um.eprints.430112023-10-05T03:30:45Z http://eprints.um.edu.my/43011/ In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants Ibrahim, Mahmoud Z. Halilu, Ahmed Sarhan, Ahmed A. D. Kuo, T. Y. Yusuf, Farazila Shaikh, M. O. Hamdi, M. TA Engineering (General). Civil engineering (General) The commonly used metallic biomaterials fail to prove durability for orthopedics due to their lack of biocompatibility and poor bioactivity which weakens the bonding to bones. Metallic glasses (MGs) have attracted attention as an alternative biomaterial for orthopedics owing to their superior mechanical properties and acceptable biocompatibility. Nevertheless, their uses are limited due to geometrical constraints and brittleness. In this research, the in-vitro bioactivity of laser cladded FeCrMoCB MG on nickel-free stainless-steel was investigated. The proposed MG coating exhibited a remarkable in-vitro bioactivity behavior without prior treatment after immersion in simulated body fluid which is a key factor for better osseointegration. The surface morphology showed that apatite nucleated from the first day and completely covered the surface after 21 days. The energy dispersive spectroscopy spectra showed an increase in the Ca/P ratio from 0.51 at 3 days to 1.61 at 21 days, thus approaching the stoichiometric ratio of bone apatite. The infra-red examination revealed the existence of Ca+2, PO4-2 and OH- indicating the nucleation of brushite and B-type apatite. Additionally, the X-ray diffraction examination revealed the existence of amorphous and nanocrystalline calcium phosphates. These results show the potential of FeCrMoCB MGs as a promising bioactive coating for excellent osseointegration of metallic implants with bone tissue. Elsevier 2022-04 Article PeerReviewed Ibrahim, Mahmoud Z. and Halilu, Ahmed and Sarhan, Ahmed A. D. and Kuo, T. Y. and Yusuf, Farazila and Shaikh, M. O. and Hamdi, M. (2022) In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants. Medical Engineering & Physics, 102. ISSN 1350-4533, DOI https://doi.org/10.1016/j.medengphy.2022.103782 <https://doi.org/10.1016/j.medengphy.2022.103782>. 10.1016/j.medengphy.2022.103782
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	TA Engineering (General). Civil engineering (General)
spellingShingle	TA Engineering (General). Civil engineering (General) Ibrahim, Mahmoud Z. Halilu, Ahmed Sarhan, Ahmed A. D. Kuo, T. Y. Yusuf, Farazila Shaikh, M. O. Hamdi, M. In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
description	The commonly used metallic biomaterials fail to prove durability for orthopedics due to their lack of biocompatibility and poor bioactivity which weakens the bonding to bones. Metallic glasses (MGs) have attracted attention as an alternative biomaterial for orthopedics owing to their superior mechanical properties and acceptable biocompatibility. Nevertheless, their uses are limited due to geometrical constraints and brittleness. In this research, the in-vitro bioactivity of laser cladded FeCrMoCB MG on nickel-free stainless-steel was investigated. The proposed MG coating exhibited a remarkable in-vitro bioactivity behavior without prior treatment after immersion in simulated body fluid which is a key factor for better osseointegration. The surface morphology showed that apatite nucleated from the first day and completely covered the surface after 21 days. The energy dispersive spectroscopy spectra showed an increase in the Ca/P ratio from 0.51 at 3 days to 1.61 at 21 days, thus approaching the stoichiometric ratio of bone apatite. The infra-red examination revealed the existence of Ca+2, PO4-2 and OH- indicating the nucleation of brushite and B-type apatite. Additionally, the X-ray diffraction examination revealed the existence of amorphous and nanocrystalline calcium phosphates. These results show the potential of FeCrMoCB MGs as a promising bioactive coating for excellent osseointegration of metallic implants with bone tissue.
format	Article
author	Ibrahim, Mahmoud Z. Halilu, Ahmed Sarhan, Ahmed A. D. Kuo, T. Y. Yusuf, Farazila Shaikh, M. O. Hamdi, M.
author_facet	Ibrahim, Mahmoud Z. Halilu, Ahmed Sarhan, Ahmed A. D. Kuo, T. Y. Yusuf, Farazila Shaikh, M. O. Hamdi, M.
author_sort	Ibrahim, Mahmoud Z.
title	In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
title_short	In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
title_full	In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
title_fullStr	In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
title_full_unstemmed	In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
title_sort	in-vitro viability of laser cladded fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants
publisher	Elsevier
publishDate	2022
url	http://eprints.um.edu.my/43011/
_version_	1781704665460637696
score	13.251813

In-vitro viability of laser cladded Fe-based metallic glass as a promising bioactive material for improved osseointegration of orthopedic implants

Similar Items