Optimal control of cancer chemotherapy with delays and state constraints
A mathematical model of cancer chemotherapy is considered as an optimal control problem with the objective of either minimizing a weighted sum of tumor cells and drug dosage or the terminal tumor volume. The control process is subject to three state constraints involving an upper bound on drug toxic...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Springer/Plenum Publishers
2022
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/41702/ |
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