Nudix Hydroxylase 15 mutations strongly predict thiopurine-induced leukopenia across different Asian ethnicities: Implications for screening in a diverse population
Background and AimsThiopurines, which are immunosuppressive drugs for maintaining remission for inflammatory bowel disease, are known to cause myelotoxicity in patients with Nudix Hydroxylase 15 (NUDT15) genetic variants in some Asian countries with monoethnic populations. We aimed to investigate th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Published: |
Frontiers Media SA
2022
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/41541/ |
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