Protein-ligand identification and in vitro inhibitory effects of cathine on 11 major human drug metabolizing cytochrome P450s
Cathine is the stable form of cathinone, the major active compound found in khat (Catha edulis Forsk) plant. Khat was found to inhibit major phase I drug metabolizing cytochrome P450 (CYP) enzyme activities in vitro and in vivo. With the upsurge of khat consumption and the potential use of cathine t...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Sage
2022
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/41445/ |
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