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Nipah virus: a recently emergent deadly paramyxovirus

A paramyxovirus virus termed Nipah virus has been identified as the etiologic agent of an outbreak of severe encephalitis in people with close contact exposure to pigs in Malaysia and Singapore. The outbreak was first noted in late September 1998 and by mid-June 1999, more than 265 encephalitis case...

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Main Authors:	Chua, K.B., Bellini, W.J., Rota, P.A., Harcourt, B.H., Tamin, A., Lam, S.K., Ksiazek, T.G., Rollin, P.E., Zaki, S.R., Shieh, W., Goldsmith, C.S., Gubler, D.J., Roehrig, J.T., Eaton, B., Gould, A.R., Olson, J., Field, H., Daniels, P., Ling, A.E., Peters, C.J., Anderson, L.J., Mahy, B.W.
Format:	Article
Published:	American Association for the Advancement of Science 2000
Subjects:	R Medicine (General)
Online Access:	http://eprints.um.edu.my/410/ http://science.sciencemag.org/content/288/5470/1432.long
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spelling	my.um.eprints.4102018-10-23T06:38:39Z http://eprints.um.edu.my/410/ Nipah virus: a recently emergent deadly paramyxovirus Chua, K.B. Bellini, W.J. Rota, P.A. Harcourt, B.H. Tamin, A. Lam, S.K. Ksiazek, T.G. Rollin, P.E. Zaki, S.R. Shieh, W. Goldsmith, C.S. Gubler, D.J. Roehrig, J.T. Eaton, B. Gould, A.R. Olson, J. Field, H. Daniels, P. Ling, A.E. Peters, C.J. Anderson, L.J. Mahy, B.W. R Medicine (General) A paramyxovirus virus termed Nipah virus has been identified as the etiologic agent of an outbreak of severe encephalitis in people with close contact exposure to pigs in Malaysia and Singapore. The outbreak was first noted in late September 1998 and by mid-June 1999, more than 265 encephalitis cases, including 105 deaths, had been reported in Malaysia, and 11 cases of encephalitis or respiratory illness with one death had been reported in Singapore. Electron microscopic, serologic, and genetic studies indicate that this virus belongs to the family Paramyxoviridae and is most closely related to the recently discovered Hendra virus. We suggest that these two viruses are representative of a new genus within the family Paramyxoviridae. Like Hendra virus, Nipah virus is unusual among the paramyxoviruses in its ability to infect and cause potentially fatal disease in a number of host species, including humans. American Association for the Advancement of Science 2000-05-26 Article PeerReviewed Chua, K.B. and Bellini, W.J. and Rota, P.A. and Harcourt, B.H. and Tamin, A. and Lam, S.K. and Ksiazek, T.G. and Rollin, P.E. and Zaki, S.R. and Shieh, W. and Goldsmith, C.S. and Gubler, D.J. and Roehrig, J.T. and Eaton, B. and Gould, A.R. and Olson, J. and Field, H. and Daniels, P. and Ling, A.E. and Peters, C.J. and Anderson, L.J. and Mahy, B.W. (2000) Nipah virus: a recently emergent deadly paramyxovirus. Science, 288 (5470). pp. 1432-1435. ISSN 1095-9203 http://science.sciencemag.org/content/288/5470/1432.long doi:10.1126/science.288.5470.1432
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	R Medicine (General)
spellingShingle	R Medicine (General) Chua, K.B. Bellini, W.J. Rota, P.A. Harcourt, B.H. Tamin, A. Lam, S.K. Ksiazek, T.G. Rollin, P.E. Zaki, S.R. Shieh, W. Goldsmith, C.S. Gubler, D.J. Roehrig, J.T. Eaton, B. Gould, A.R. Olson, J. Field, H. Daniels, P. Ling, A.E. Peters, C.J. Anderson, L.J. Mahy, B.W. Nipah virus: a recently emergent deadly paramyxovirus
description	A paramyxovirus virus termed Nipah virus has been identified as the etiologic agent of an outbreak of severe encephalitis in people with close contact exposure to pigs in Malaysia and Singapore. The outbreak was first noted in late September 1998 and by mid-June 1999, more than 265 encephalitis cases, including 105 deaths, had been reported in Malaysia, and 11 cases of encephalitis or respiratory illness with one death had been reported in Singapore. Electron microscopic, serologic, and genetic studies indicate that this virus belongs to the family Paramyxoviridae and is most closely related to the recently discovered Hendra virus. We suggest that these two viruses are representative of a new genus within the family Paramyxoviridae. Like Hendra virus, Nipah virus is unusual among the paramyxoviruses in its ability to infect and cause potentially fatal disease in a number of host species, including humans.
format	Article
author	Chua, K.B. Bellini, W.J. Rota, P.A. Harcourt, B.H. Tamin, A. Lam, S.K. Ksiazek, T.G. Rollin, P.E. Zaki, S.R. Shieh, W. Goldsmith, C.S. Gubler, D.J. Roehrig, J.T. Eaton, B. Gould, A.R. Olson, J. Field, H. Daniels, P. Ling, A.E. Peters, C.J. Anderson, L.J. Mahy, B.W.
author_facet	Chua, K.B. Bellini, W.J. Rota, P.A. Harcourt, B.H. Tamin, A. Lam, S.K. Ksiazek, T.G. Rollin, P.E. Zaki, S.R. Shieh, W. Goldsmith, C.S. Gubler, D.J. Roehrig, J.T. Eaton, B. Gould, A.R. Olson, J. Field, H. Daniels, P. Ling, A.E. Peters, C.J. Anderson, L.J. Mahy, B.W.
author_sort	Chua, K.B.
title	Nipah virus: a recently emergent deadly paramyxovirus
title_short	Nipah virus: a recently emergent deadly paramyxovirus
title_full	Nipah virus: a recently emergent deadly paramyxovirus
title_fullStr	Nipah virus: a recently emergent deadly paramyxovirus
title_full_unstemmed	Nipah virus: a recently emergent deadly paramyxovirus
title_sort	nipah virus: a recently emergent deadly paramyxovirus
publisher	American Association for the Advancement of Science
publishDate	2000
url	http://eprints.um.edu.my/410/ http://science.sciencemag.org/content/288/5470/1432.long
_version_	1643686567856832512
score	13.211869

Nipah virus: a recently emergent deadly paramyxovirus

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