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Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device

Objectives To evaluate the performance and utility of a time-temperature indicator (TTI) to determine the cumulative exposure time (CET) of red cell components (RCC) to temperatures above 10 degrees C occurring within and outside the transfusion laboratory. Background and Objectives Blood centres of...

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Main Authors: Cheng, Jian Yuan, Samudram, Hemalatha, Lee, Christina Lai Ling, Nadarajan, Veera Sekaran
Format: Article
Published: Wiley 2022
Subjects:
R Medicine (General)
Online Access:http://eprints.um.edu.my/40387/
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spelling my.um.eprints.403872023-11-22T06:32:00Z http://eprints.um.edu.my/40387/ Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device Cheng, Jian Yuan Samudram, Hemalatha Lee, Christina Lai Ling Nadarajan, Veera Sekaran R Medicine (General) Objectives To evaluate the performance and utility of a time-temperature indicator (TTI) to determine the cumulative exposure time (CET) of red cell components (RCC) to temperatures above 10 degrees C occurring within and outside the transfusion laboratory. Background and Objectives Blood centres often use the `30 or 60-min rule' for accepting RCC exposed to room temperature (RT) back into inventory. Effective monitoring of these temperature deviations is however lacking. Materials and Methods A Timestrip PLUS (R) TP153 10 degrees C (TS + 10) TTI was attached to RCC units after preparation of the unit in the blood bank or on issue to the ward, to track the CET > 10 degrees C during laboratory processing and outside the transfusion laboratory. Results The mean CET of 153 RCC tracked within the laboratory was 56 min. Sixty-four (41.8%) and 34 (22.2%) of RCC had core temperature (CT) >10 degrees C for more than 30 and 60 min, respectively. Among the 69 RCC that were returned unused, 27 (39.1%), 17 (24.6%) and 5 (7.2%) RCC units had CT >10 degrees C for more than 30, 60 and 120 min respectively. Conclusion A large proportion of RCC have CT >10 degrees C exceeding 30 min during handling within the transfusion laboratory, as well as when RCC are returned unused from transfusion locations. Corrective measures should be implemented to better manage the cold chain to avoid undesirable consequences to blood transfusion. A temperature sensitive device that can also indicate CET can be employed to objectively monitor the period that RCC remained at a CT that exceeds 10 degrees C. Wiley 2022-12 Article PeerReviewed Cheng, Jian Yuan and Samudram, Hemalatha and Lee, Christina Lai Ling and Nadarajan, Veera Sekaran (2022) Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device. Transfusion Medicine, 32 (6). pp. 484-491. ISSN 0958-7578, DOI https://doi.org/10.1111/tme.12924 <https://doi.org/10.1111/tme.12924>. 10.1111/tme.12924
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Cheng, Jian Yuan
Samudram, Hemalatha
Lee, Christina Lai Ling
Nadarajan, Veera Sekaran
Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
description Objectives To evaluate the performance and utility of a time-temperature indicator (TTI) to determine the cumulative exposure time (CET) of red cell components (RCC) to temperatures above 10 degrees C occurring within and outside the transfusion laboratory. Background and Objectives Blood centres often use the `30 or 60-min rule' for accepting RCC exposed to room temperature (RT) back into inventory. Effective monitoring of these temperature deviations is however lacking. Materials and Methods A Timestrip PLUS (R) TP153 10 degrees C (TS + 10) TTI was attached to RCC units after preparation of the unit in the blood bank or on issue to the ward, to track the CET > 10 degrees C during laboratory processing and outside the transfusion laboratory. Results The mean CET of 153 RCC tracked within the laboratory was 56 min. Sixty-four (41.8%) and 34 (22.2%) of RCC had core temperature (CT) >10 degrees C for more than 30 and 60 min, respectively. Among the 69 RCC that were returned unused, 27 (39.1%), 17 (24.6%) and 5 (7.2%) RCC units had CT >10 degrees C for more than 30, 60 and 120 min respectively. Conclusion A large proportion of RCC have CT >10 degrees C exceeding 30 min during handling within the transfusion laboratory, as well as when RCC are returned unused from transfusion locations. Corrective measures should be implemented to better manage the cold chain to avoid undesirable consequences to blood transfusion. A temperature sensitive device that can also indicate CET can be employed to objectively monitor the period that RCC remained at a CT that exceeds 10 degrees C.
format Article
author Cheng, Jian Yuan
Samudram, Hemalatha
Lee, Christina Lai Ling
Nadarajan, Veera Sekaran
author_facet Cheng, Jian Yuan
Samudram, Hemalatha
Lee, Christina Lai Ling
Nadarajan, Veera Sekaran
author_sort Cheng, Jian Yuan
title Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
title_short Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
title_full Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
title_fullStr Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
title_full_unstemmed Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
title_sort deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device
publisher Wiley
publishDate 2022
url http://eprints.um.edu.my/40387/
_version_ 1783876706562473984
score 13.211869

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