Does pharmacological treatment of depression in people with a primary brain tumour bring any benefits? A Cochrane Review summary with commentary

BACKGROUND: Persons with primary brain tumour can suffer from depression. Depression may hinder rehabilitation intervention leading to further deterioration of patient's health and functioning. OBJECTIVE: The Cochrane Review aimed to assess the effectiveness and adverse effects of pharmacologic...

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Bibliographic Details
Main Authors: Mazlan, Mazlina, Engkasan, Julia Patrick
Format: Article
Published: IOS Press 2022
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Online Access:http://eprints.um.edu.my/39604/
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Summary:BACKGROUND: Persons with primary brain tumour can suffer from depression. Depression may hinder rehabilitation intervention leading to further deterioration of patient's health and functioning. OBJECTIVE: The Cochrane Review aimed to assess the effectiveness and adverse effects of pharmacological treatment of depression in people with a primary brain tumour. METHODS: A Cochrane Review by Beevers et al. was summarized with comments. RESULTS: The reviewdid not find any eligible studies from the 2090 studies screened which included randomized controlled trials, cohort studies and case-control studies. CONCLUSIONS: There is no high-quality evidence as to whether pharmacological treatments for depression in people with primary brain tumours are either effective or harmful.