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Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide

Carbonate apatite (CO(3)Ap) is a bioceramic material with excellent properties for bone and dentin regeneration. To enhance its mechanical strength and bioactivity, silica calcium phosphate composites (Si-CaP) and calcium hydroxide (Ca(OH)(2)) were added to CO(3)Ap cement. The aim of this study was...

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Main Authors: Cahyanto, Arief, Liemidia, Michella, Karlina, Elin, Zakaria, Myrna Nurlatifah, Shariff, Khairul Anuar, Sukotjo, Cortino, El-Ghannam, Ahmed
Format: Article
Published: MDPI 2023
Subjects:
RK Dentistry
Online Access:http://eprints.um.edu.my/38485/
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spelling my.um.eprints.384852023-07-06T02:46:18Z http://eprints.um.edu.my/38485/ Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide Cahyanto, Arief Liemidia, Michella Karlina, Elin Zakaria, Myrna Nurlatifah Shariff, Khairul Anuar Sukotjo, Cortino El-Ghannam, Ahmed RK Dentistry Carbonate apatite (CO(3)Ap) is a bioceramic material with excellent properties for bone and dentin regeneration. To enhance its mechanical strength and bioactivity, silica calcium phosphate composites (Si-CaP) and calcium hydroxide (Ca(OH)(2)) were added to CO(3)Ap cement. The aim of this study was to investigate the effect of Si-CaP and Ca(OH)(2) on the mechanical properties in terms of the compressive strength and biological characteristics of CO(3)Ap cement, specifically the formation of an apatite layer and the exchange of Ca, P, and Si elements. Five groups were prepared by mixing CO(3)Ap powder consisting of dicalcium phosphate anhydrous and vaterite powder added by varying ratios of Si-CaP and Ca(OH)(2) and 0.2 mol/L Na2HPO4 as a liquid. All groups underwent compressive strength testing, and the group with the highest strength was evaluated for bioactivity by soaking it in simulated body fluid (SBF) for one, seven, 14, and 21 days. The group that added 3% Si-CaP and 7% Ca(OH)(2) had the highest compressive strength among the groups. SEM analysis revealed the formation of needle-like apatite crystals from the first day of SBF soaking, and EDS analysis indicated an increase in Ca, P, and Si elements. XRD and FTIR analyses confirmed the presence of apatite. This combination of additives improved the compressive strength and showed the good bioactivity performance of CO(3)Ap cement, making it a potential biomaterial for bone and dental engineering applications. MDPI 2023-03 Article PeerReviewed Cahyanto, Arief and Liemidia, Michella and Karlina, Elin and Zakaria, Myrna Nurlatifah and Shariff, Khairul Anuar and Sukotjo, Cortino and El-Ghannam, Ahmed (2023) Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide. Materials, 16 (5). ISSN 1996-1944, DOI https://doi.org/10.3390/ma16052071 <https://doi.org/10.3390/ma16052071>. 10.3390/ma16052071
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic RK Dentistry
spellingShingle RK Dentistry
Cahyanto, Arief
Liemidia, Michella
Karlina, Elin
Zakaria, Myrna Nurlatifah
Shariff, Khairul Anuar
Sukotjo, Cortino
El-Ghannam, Ahmed
Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
description Carbonate apatite (CO(3)Ap) is a bioceramic material with excellent properties for bone and dentin regeneration. To enhance its mechanical strength and bioactivity, silica calcium phosphate composites (Si-CaP) and calcium hydroxide (Ca(OH)(2)) were added to CO(3)Ap cement. The aim of this study was to investigate the effect of Si-CaP and Ca(OH)(2) on the mechanical properties in terms of the compressive strength and biological characteristics of CO(3)Ap cement, specifically the formation of an apatite layer and the exchange of Ca, P, and Si elements. Five groups were prepared by mixing CO(3)Ap powder consisting of dicalcium phosphate anhydrous and vaterite powder added by varying ratios of Si-CaP and Ca(OH)(2) and 0.2 mol/L Na2HPO4 as a liquid. All groups underwent compressive strength testing, and the group with the highest strength was evaluated for bioactivity by soaking it in simulated body fluid (SBF) for one, seven, 14, and 21 days. The group that added 3% Si-CaP and 7% Ca(OH)(2) had the highest compressive strength among the groups. SEM analysis revealed the formation of needle-like apatite crystals from the first day of SBF soaking, and EDS analysis indicated an increase in Ca, P, and Si elements. XRD and FTIR analyses confirmed the presence of apatite. This combination of additives improved the compressive strength and showed the good bioactivity performance of CO(3)Ap cement, making it a potential biomaterial for bone and dental engineering applications.
format Article
author Cahyanto, Arief
Liemidia, Michella
Karlina, Elin
Zakaria, Myrna Nurlatifah
Shariff, Khairul Anuar
Sukotjo, Cortino
El-Ghannam, Ahmed
author_facet Cahyanto, Arief
Liemidia, Michella
Karlina, Elin
Zakaria, Myrna Nurlatifah
Shariff, Khairul Anuar
Sukotjo, Cortino
El-Ghannam, Ahmed
author_sort Cahyanto, Arief
title Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
title_short Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
title_full Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
title_fullStr Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
title_full_unstemmed Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
title_sort bioactive carbonate apatite cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide
publisher MDPI
publishDate 2023
url http://eprints.um.edu.my/38485/
_version_ 1772811754047275008
score 13.211869

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