Dihydroorotate dehydrogenase inhibitors promote cell cycle arrest and disrupt mitochondria bioenergetics in Ramos cells

Background: The re-emerging of targeting Dihydroorotate Dehydrogenase (DHODH) in cancer treatment particularly Acute Myelogenous Leukemia (AML) has corroborated the substantial role of DHODH in cancer and received the attention of many pharmaceutical industries. Objective: The effects of Brequinar S...

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Bibliographic Details
Main Authors: Kadir, Mohamad F. A., Othman, Shatrah, Nellore, Kavitha
Format: Article
Published: Bentham Science Publ Ltd 2020
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Online Access:http://eprints.um.edu.my/37049/
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