Staff View: Establishment of Asia-Pacific network for enterovirus surveillance

Establishment of Asia-Pacific network for enterovirus surveillance

Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affect millions of children each year. Most human enteroviruses cause self-limited infections except polio-viruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and several echoviruses (Echo) and c...

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Main Authors:	Chiu, Mu-Lin, Luo, Shu-Ting, Chen, Ya-Yen, Chung, Wan Yu, Duong, Veasna, Dussart, Philippe, Chan, Yoke-Fun, Perera, David, Ooi, Mong How, Thao, Nguyen Thi Thanh, Truong, Huu Khanh, Lee, Min-Shi
Format:	Article
Published:	MDPI 2020
Subjects:	QR Microbiology
Online Access:	http://eprints.um.edu.my/36959/
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spelling	my.um.eprints.369592023-11-30T07:06:51Z http://eprints.um.edu.my/36959/ Establishment of Asia-Pacific network for enterovirus surveillance Chiu, Mu-Lin Luo, Shu-Ting Chen, Ya-Yen Chung, Wan Yu Duong, Veasna Dussart, Philippe Chan, Yoke-Fun Perera, David Ooi, Mong How Thao, Nguyen Thi Thanh Truong, Huu Khanh Lee, Min-Shi QR Microbiology Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affect millions of children each year. Most human enteroviruses cause self-limited infections except polio-viruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and several echoviruses (Echo) and cox-sackieviruses (CV). Especially, EV-A71 has repeatedly caused large-scale outbreaks in the Asia-Pacific region since 1997. Some Asian countries have experienced cyclical outbreaks of severe EV-A71 infections and initiated development of EV-A71 vaccines. Five EV-A71 vaccine candidates have been clinically evaluated and three of them were approved for marketing in China. However, none of the China-approved products seek marketing approval in other countries. This situation supports a role for collaboration among Asian countries to facilitate clinical trials and licensure of EV-A71 vaccines. Additionally, enterovirus D68 outbreaks have been reported in the US and Taiwan currently and caused severe complications and deaths. Hence, an Asia-Pacific Network for Enterovirus Surveillance (APNES) has been established to estimate disease burden, understand virus evolution, and facilitate vaccine development through harmonizing laboratory diagnosis and data collection. Founded in 2017, the APNES is comprised of internationally recognized experts in the field of enterovirus in Asian countries working to raise awareness of this potentially fatal and debilitating disease. This article demonstrated the summaries of the first expert meeting, 2017 International Workshop on Enterovirus Surveillance and Vaccine Development, held by APNES in Taipei, Taiwan, March 2017. MDPI 2020-01 Article PeerReviewed Chiu, Mu-Lin and Luo, Shu-Ting and Chen, Ya-Yen and Chung, Wan Yu and Duong, Veasna and Dussart, Philippe and Chan, Yoke-Fun and Perera, David and Ooi, Mong How and Thao, Nguyen Thi Thanh and Truong, Huu Khanh and Lee, Min-Shi (2020) Establishment of Asia-Pacific network for enterovirus surveillance. Vaccines, 38 (1). pp. 1-9. ISSN 2076-393X, DOI https://doi.org/10.1016/j.vaccine.2019.09.111 <https://doi.org/10.1016/j.vaccine.2019.09.111>. 10.1016/j.vaccine.2019.09.111
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	QR Microbiology
spellingShingle	QR Microbiology Chiu, Mu-Lin Luo, Shu-Ting Chen, Ya-Yen Chung, Wan Yu Duong, Veasna Dussart, Philippe Chan, Yoke-Fun Perera, David Ooi, Mong How Thao, Nguyen Thi Thanh Truong, Huu Khanh Lee, Min-Shi Establishment of Asia-Pacific network for enterovirus surveillance
description	Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affect millions of children each year. Most human enteroviruses cause self-limited infections except polio-viruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and several echoviruses (Echo) and cox-sackieviruses (CV). Especially, EV-A71 has repeatedly caused large-scale outbreaks in the Asia-Pacific region since 1997. Some Asian countries have experienced cyclical outbreaks of severe EV-A71 infections and initiated development of EV-A71 vaccines. Five EV-A71 vaccine candidates have been clinically evaluated and three of them were approved for marketing in China. However, none of the China-approved products seek marketing approval in other countries. This situation supports a role for collaboration among Asian countries to facilitate clinical trials and licensure of EV-A71 vaccines. Additionally, enterovirus D68 outbreaks have been reported in the US and Taiwan currently and caused severe complications and deaths. Hence, an Asia-Pacific Network for Enterovirus Surveillance (APNES) has been established to estimate disease burden, understand virus evolution, and facilitate vaccine development through harmonizing laboratory diagnosis and data collection. Founded in 2017, the APNES is comprised of internationally recognized experts in the field of enterovirus in Asian countries working to raise awareness of this potentially fatal and debilitating disease. This article demonstrated the summaries of the first expert meeting, 2017 International Workshop on Enterovirus Surveillance and Vaccine Development, held by APNES in Taipei, Taiwan, March 2017.
format	Article
author	Chiu, Mu-Lin Luo, Shu-Ting Chen, Ya-Yen Chung, Wan Yu Duong, Veasna Dussart, Philippe Chan, Yoke-Fun Perera, David Ooi, Mong How Thao, Nguyen Thi Thanh Truong, Huu Khanh Lee, Min-Shi
author_facet	Chiu, Mu-Lin Luo, Shu-Ting Chen, Ya-Yen Chung, Wan Yu Duong, Veasna Dussart, Philippe Chan, Yoke-Fun Perera, David Ooi, Mong How Thao, Nguyen Thi Thanh Truong, Huu Khanh Lee, Min-Shi
author_sort	Chiu, Mu-Lin
title	Establishment of Asia-Pacific network for enterovirus surveillance
title_short	Establishment of Asia-Pacific network for enterovirus surveillance
title_full	Establishment of Asia-Pacific network for enterovirus surveillance
title_fullStr	Establishment of Asia-Pacific network for enterovirus surveillance
title_full_unstemmed	Establishment of Asia-Pacific network for enterovirus surveillance
title_sort	establishment of asia-pacific network for enterovirus surveillance
publisher	MDPI
publishDate	2020
url	http://eprints.um.edu.my/36959/
_version_	1784511835980955648
score	13.211869

Establishment of Asia-Pacific network for enterovirus surveillance

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