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A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering

The need of tissue and organ for transplantation to repair or replace damaged tissues is significantly higher than the availability of donated organs. Tissue engineering that develops functional substitutes for damaged tissues and organs via employing a combination of 3D biomaterials, supportive bio...

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Main Authors: Tran, Huong D. N., Park, Ki Dong, Ching, Yern Chee, Huynh, Cong, Nguyen, Dai Hai
Format: Article
Published: Korean Society of Industrial Engineering Chemistry 2020
Subjects:
TP Chemical technology
Online Access:http://eprints.um.edu.my/36395/
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spelling my.um.eprints.363952024-10-28T07:11:10Z http://eprints.um.edu.my/36395/ A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering Tran, Huong D. N. Park, Ki Dong Ching, Yern Chee Huynh, Cong Nguyen, Dai Hai TP Chemical technology The need of tissue and organ for transplantation to repair or replace damaged tissues is significantly higher than the availability of donated organs. Tissue engineering that develops functional substitutes for damaged tissues and organs via employing a combination of 3D biomaterials, supportive bioactive molecules, and/or living cells followed by in vitro culture and/or in vivo implantation, therefore, has attracted much attention in engineering the substitutes. Among 3D biomaterials, hydrogel materials have been extensively explored as matrices for skeletal regeneration because of their biocompatibility, tailorable mechanical properties, flexibility in fabrication, and ability to encapsulate cells and bioactive factors for their sustained, localized and controlled presentation. This review focuses on polymeric hydrogels and theirs composites for both bone and cartilage regeneration, including required properties, design and fabrication, functioned as bared biomaterials or delivery vehicles of bioactive molecules and/or cells together with remaining challenges and future perspectives, emphasizing on the last few years. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. Korean Society of Industrial Engineering Chemistry 2020-09 Article PeerReviewed Tran, Huong D. N. and Park, Ki Dong and Ching, Yern Chee and Huynh, Cong and Nguyen, Dai Hai (2020) A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering. Journal of Industrial and Engineering Chemistry, 89. pp. 58-82. ISSN 1226-086X, DOI https://doi.org/10.1016/j.jiec.2020.06.017 <https://doi.org/10.1016/j.jiec.2020.06.017>. 10.1016/j.jiec.2020.06.017
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Tran, Huong D. N.
Park, Ki Dong
Ching, Yern Chee
Huynh, Cong
Nguyen, Dai Hai
A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
description The need of tissue and organ for transplantation to repair or replace damaged tissues is significantly higher than the availability of donated organs. Tissue engineering that develops functional substitutes for damaged tissues and organs via employing a combination of 3D biomaterials, supportive bioactive molecules, and/or living cells followed by in vitro culture and/or in vivo implantation, therefore, has attracted much attention in engineering the substitutes. Among 3D biomaterials, hydrogel materials have been extensively explored as matrices for skeletal regeneration because of their biocompatibility, tailorable mechanical properties, flexibility in fabrication, and ability to encapsulate cells and bioactive factors for their sustained, localized and controlled presentation. This review focuses on polymeric hydrogels and theirs composites for both bone and cartilage regeneration, including required properties, design and fabrication, functioned as bared biomaterials or delivery vehicles of bioactive molecules and/or cells together with remaining challenges and future perspectives, emphasizing on the last few years. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
format Article
author Tran, Huong D. N.
Park, Ki Dong
Ching, Yern Chee
Huynh, Cong
Nguyen, Dai Hai
author_facet Tran, Huong D. N.
Park, Ki Dong
Ching, Yern Chee
Huynh, Cong
Nguyen, Dai Hai
author_sort Tran, Huong D. N.
title A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
title_short A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
title_full A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
title_fullStr A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
title_full_unstemmed A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering
title_sort comprehensive review on polymeric hydrogel and its composite: matrices of choice for bone and cartilage tissue engineering
publisher Korean Society of Industrial Engineering Chemistry
publishDate 2020
url http://eprints.um.edu.my/36395/
_version_ 1814933196426444800
score 13.222552

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