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Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)

As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in thes...

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Main Authors:	Takeshita, Akihiro, Watanabe, Hiroko, Yamada, Chiaki, Nadarajan, Veera Sekaran, Permpikul, Parichart, Sinkitjasub, Attapong, Natalie, Chan Pui Ha, Zhao, Shuming, Han, Kyou Sup, Kim, Dae Won, Suh, Jang Soo, Kim, Hyun Ok, Kawabata, Kinuyo, Ishimaru, Ken, Ohtomo, Naoki, Yamada, Naotomo, Tomoda, Yutaka, Yurugi, Kimiko, Ohto, Hitoshi
Format:	Article
Published:	PERGAMON-ELSEVIER SCIENCE LTD 2020
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/36383/
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spelling	my.um.eprints.363832023-12-28T13:38:42Z http://eprints.um.edu.my/36383/ Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP) Takeshita, Akihiro Watanabe, Hiroko Yamada, Chiaki Nadarajan, Veera Sekaran Permpikul, Parichart Sinkitjasub, Attapong Natalie, Chan Pui Ha Zhao, Shuming Han, Kyou Sup Kim, Dae Won Suh, Jang Soo Kim, Hyun Ok Kawabata, Kinuyo Ishimaru, Ken Ohtomo, Naoki Yamada, Naotomo Tomoda, Yutaka Yurugi, Kimiko Ohto, Hitoshi R Medicine As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in these cases were as follows: anti-E, 26.8%; anti-Lea, 20.0%; anti-P1, 7.1%; anti-M, 6.4%; anti-Mia, 5.6%; anti-c + E, 5.6%; anti-Leb, 4.6%; anti-D, 2.8%; anti-Fyb, 2.6%; anti-Lea+Leb, 2.5%; anti-Dia, 2.0%; and others. For pregnant patients, anti-D (12.7%) was statistically more frequent. For transfused patients, anti-E (37.3%), anti-c + E (9.5%), anti-C + e (3.3%) and anti-Jka (3.1%) were significantly more frequent. PERGAMON-ELSEVIER SCIENCE LTD 2020-10 Article PeerReviewed Takeshita, Akihiro and Watanabe, Hiroko and Yamada, Chiaki and Nadarajan, Veera Sekaran and Permpikul, Parichart and Sinkitjasub, Attapong and Natalie, Chan Pui Ha and Zhao, Shuming and Han, Kyou Sup and Kim, Dae Won and Suh, Jang Soo and Kim, Hyun Ok and Kawabata, Kinuyo and Ishimaru, Ken and Ohtomo, Naoki and Yamada, Naotomo and Tomoda, Yutaka and Yurugi, Kimiko and Ohto, Hitoshi (2020) Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP). TRANSFUSION AND APHERESIS SCIENCE, 59 (5). ISSN 14730502, DOI https://doi.org/10.1016/j.transci.2020.102944 <https://doi.org/10.1016/j.transci.2020.102944>. 10.1016/j.transci.2020.102944
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	R Medicine
spellingShingle	R Medicine Takeshita, Akihiro Watanabe, Hiroko Yamada, Chiaki Nadarajan, Veera Sekaran Permpikul, Parichart Sinkitjasub, Attapong Natalie, Chan Pui Ha Zhao, Shuming Han, Kyou Sup Kim, Dae Won Suh, Jang Soo Kim, Hyun Ok Kawabata, Kinuyo Ishimaru, Ken Ohtomo, Naoki Yamada, Naotomo Tomoda, Yutaka Yurugi, Kimiko Ohto, Hitoshi Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
description	As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in these cases were as follows: anti-E, 26.8%; anti-Lea, 20.0%; anti-P1, 7.1%; anti-M, 6.4%; anti-Mia, 5.6%; anti-c + E, 5.6%; anti-Leb, 4.6%; anti-D, 2.8%; anti-Fyb, 2.6%; anti-Lea+Leb, 2.5%; anti-Dia, 2.0%; and others. For pregnant patients, anti-D (12.7%) was statistically more frequent. For transfused patients, anti-E (37.3%), anti-c + E (9.5%), anti-C + e (3.3%) and anti-Jka (3.1%) were significantly more frequent.
format	Article
author	Takeshita, Akihiro Watanabe, Hiroko Yamada, Chiaki Nadarajan, Veera Sekaran Permpikul, Parichart Sinkitjasub, Attapong Natalie, Chan Pui Ha Zhao, Shuming Han, Kyou Sup Kim, Dae Won Suh, Jang Soo Kim, Hyun Ok Kawabata, Kinuyo Ishimaru, Ken Ohtomo, Naoki Yamada, Naotomo Tomoda, Yutaka Yurugi, Kimiko Ohto, Hitoshi
author_facet	Takeshita, Akihiro Watanabe, Hiroko Yamada, Chiaki Nadarajan, Veera Sekaran Permpikul, Parichart Sinkitjasub, Attapong Natalie, Chan Pui Ha Zhao, Shuming Han, Kyou Sup Kim, Dae Won Suh, Jang Soo Kim, Hyun Ok Kawabata, Kinuyo Ishimaru, Ken Ohtomo, Naoki Yamada, Naotomo Tomoda, Yutaka Yurugi, Kimiko Ohto, Hitoshi
author_sort	Takeshita, Akihiro
title	Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
title_short	Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
title_full	Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
title_fullStr	Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
title_full_unstemmed	Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
title_sort	erythrocyte alloimmunity and genetic variance: results from the collaborative study of alloimmunity to antigen diversity in asian populations (all adp)
publisher	PERGAMON-ELSEVIER SCIENCE LTD
publishDate	2020
url	http://eprints.um.edu.my/36383/
_version_	1787133817466650624
score	13.244413

Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)

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