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Physical Modification of Bovine Amniotic Membrane for Dental Application

Collagen sponge are used as biomaterial in the field of tissue engineering to increase the life expectancy. Bovine amniotic membrane (BAM) contains collagen and growth factors that will accelerate wound healing after dental extraction procedure. The physical structure of the BAM in the form of a thi...

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Main Authors: Octarina, A., Munadziroh, E., Razak, Fathilah Abdul
Format: Article
Published: Ektodermal Displazi Grubu 2021
Subjects:
RK Dentistry
Oral surger
Online Access:http://eprints.um.edu.my/36149/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123863529&partnerID=40&md5=bfbe0f0e114bcc552b9029729f2b83a7
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spelling my.um.eprints.361492023-11-29T04:31:34Z http://eprints.um.edu.my/36149/ Physical Modification of Bovine Amniotic Membrane for Dental Application Octarina, A. Munadziroh, E. Razak, Fathilah Abdul RK Dentistry Oral surger Collagen sponge are used as biomaterial in the field of tissue engineering to increase the life expectancy. Bovine amniotic membrane (BAM) contains collagen and growth factors that will accelerate wound healing after dental extraction procedure. The physical structure of the BAM in the form of a thin sheet will be difficult when applied to the extraction socket. The aims of this study were to modify the physical structure of BAM in the form of a thin sheet into a sponge after that analyze its characteristics by SEM and FTIR. Fresh BAM was washed and divided into 2 parts. The first part in the form of sheets is immediately freeze dried. The second part was cut into pieces then added PBS in a ratio of 1:1. BAM and PBS are then blended until they form a slurry and are sticky like jelly, then freeze drying. After fabrication BAM and modified BAM, then it characterized by FTIR and SEM. The result of fabrication BAM looks like a thin sheet, while the modified BAM looks like a sponge that has a porous structure by using SEM analysis. FTIR analysis showed the collagen content in the presence of functional groups amide A, Amide B, amide I, amide II, amide III in BAM and modified BAM. In this study, modification of BAM will form a porous physical structure like a sponge without losing its collagen as main component. © 2021, Journal of International Dental and Medical Research. All Rights Reserved. Ektodermal Displazi Grubu 2021 Article PeerReviewed Octarina, A. and Munadziroh, E. and Razak, Fathilah Abdul (2021) Physical Modification of Bovine Amniotic Membrane for Dental Application. Journal of International Dental and Medical Research, 14 (4). pp. 1425-1428. ISSN 1309100X, https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123863529&partnerID=40&md5=bfbe0f0e114bcc552b9029729f2b83a7
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic RK Dentistry
Oral surger
spellingShingle RK Dentistry
Oral surger
Octarina, A.
Munadziroh, E.
Razak, Fathilah Abdul
Physical Modification of Bovine Amniotic Membrane for Dental Application
description Collagen sponge are used as biomaterial in the field of tissue engineering to increase the life expectancy. Bovine amniotic membrane (BAM) contains collagen and growth factors that will accelerate wound healing after dental extraction procedure. The physical structure of the BAM in the form of a thin sheet will be difficult when applied to the extraction socket. The aims of this study were to modify the physical structure of BAM in the form of a thin sheet into a sponge after that analyze its characteristics by SEM and FTIR. Fresh BAM was washed and divided into 2 parts. The first part in the form of sheets is immediately freeze dried. The second part was cut into pieces then added PBS in a ratio of 1:1. BAM and PBS are then blended until they form a slurry and are sticky like jelly, then freeze drying. After fabrication BAM and modified BAM, then it characterized by FTIR and SEM. The result of fabrication BAM looks like a thin sheet, while the modified BAM looks like a sponge that has a porous structure by using SEM analysis. FTIR analysis showed the collagen content in the presence of functional groups amide A, Amide B, amide I, amide II, amide III in BAM and modified BAM. In this study, modification of BAM will form a porous physical structure like a sponge without losing its collagen as main component. © 2021, Journal of International Dental and Medical Research. All Rights Reserved.
format Article
author Octarina, A.
Munadziroh, E.
Razak, Fathilah Abdul
author_facet Octarina, A.
Munadziroh, E.
Razak, Fathilah Abdul
author_sort Octarina, A.
title Physical Modification of Bovine Amniotic Membrane for Dental Application
title_short Physical Modification of Bovine Amniotic Membrane for Dental Application
title_full Physical Modification of Bovine Amniotic Membrane for Dental Application
title_fullStr Physical Modification of Bovine Amniotic Membrane for Dental Application
title_full_unstemmed Physical Modification of Bovine Amniotic Membrane for Dental Application
title_sort physical modification of bovine amniotic membrane for dental application
publisher Ektodermal Displazi Grubu
publishDate 2021
url http://eprints.um.edu.my/36149/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123863529&partnerID=40&md5=bfbe0f0e114bcc552b9029729f2b83a7
_version_ 1783876650445832192
score 13.211869

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