Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review

Coronavirus disease 2019 (COVID-19) is highly contagious and has claimed more than one million lives, besides causing hardship and disruptions. The Fleischner Society has recommended chest X-ray (CXR) in detecting cases at high risk of disease progression, for triaging suspected patients with modera...

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Main Authors: Chan, Wai Yee, Hamid, Marlina Tanty Ramli, Gowdh, Nadia Fareeda Muhammad, Rahmat, Kartini, Yaakup, Nur Adura, Chai, Chee Shee
Format: Article
Published: Bentham Science Publ Ltd 2021
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Online Access:http://eprints.um.edu.my/35462/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112124816&doi=10.2174%2f1573405616666201231103312&partnerID=40&md5=6f83f6f978542556b18675dd83e6cad6
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spelling my.um.eprints.354622023-08-24T04:18:40Z http://eprints.um.edu.my/35462/ Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review Chan, Wai Yee Hamid, Marlina Tanty Ramli Gowdh, Nadia Fareeda Muhammad Rahmat, Kartini Yaakup, Nur Adura Chai, Chee Shee R Medicine Coronavirus disease 2019 (COVID-19) is highly contagious and has claimed more than one million lives, besides causing hardship and disruptions. The Fleischner Society has recommended chest X-ray (CXR) in detecting cases at high risk of disease progression, for triaging suspected patients with moderate-to-severe illness, and for eliminating false negatives in ar-eas with high pre-test probability or limited resources. Although CXR is less sensitive than real--time reverse transcription-polymerase chain reaction (RT-PCR) in detecting mild COVID-19, it is nevertheless useful because of equipment portability, low cost and practicality in serial assessments of disease progression among hospitalized patients. Objective: This study aims to review the typical and relatively atypical CXR manifestations of COVID-19 pneumonia in a tertiary care hospital. Methods: The CXRs of 136 COVID-19 patients confirmed through real-time RT-PCR from March to May 2020 were reviewed. A literature search was performed using PubMed. Results: A total of 54 patients had abnormal CXR whilst the others were normal. Typical CXR findings included pulmonary consolidation or ground-glass opacities in a multifocal, bilateral pe-ripheral, or lower zone distribution, whereas atypical CXR features comprised cavitation and pleu-ral effusion. Conclusion: Typical findings of COVID-19 infection in chest computed tomography studies can also be seen in CXR. The presence of atypical features associated with worse disease outcome. Recognition of these features on CXR will improve the accuracy and speed of diagnosing COVID-19 patients. © 2021 Bentham Science Publishers. Bentham Science Publ Ltd 2021 Article PeerReviewed Chan, Wai Yee and Hamid, Marlina Tanty Ramli and Gowdh, Nadia Fareeda Muhammad and Rahmat, Kartini and Yaakup, Nur Adura and Chai, Chee Shee (2021) Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review. Current Medical Imaging, 17 (6). pp. 677-685. ISSN 1573-4056, DOI https://doi.org/10.2174/1573405616666201231103312 <https://doi.org/10.2174/1573405616666201231103312>. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112124816&doi=10.2174%2f1573405616666201231103312&partnerID=40&md5=6f83f6f978542556b18675dd83e6cad6 10.2174/1573405616666201231103312
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Chan, Wai Yee
Hamid, Marlina Tanty Ramli
Gowdh, Nadia Fareeda Muhammad
Rahmat, Kartini
Yaakup, Nur Adura
Chai, Chee Shee
Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
description Coronavirus disease 2019 (COVID-19) is highly contagious and has claimed more than one million lives, besides causing hardship and disruptions. The Fleischner Society has recommended chest X-ray (CXR) in detecting cases at high risk of disease progression, for triaging suspected patients with moderate-to-severe illness, and for eliminating false negatives in ar-eas with high pre-test probability or limited resources. Although CXR is less sensitive than real--time reverse transcription-polymerase chain reaction (RT-PCR) in detecting mild COVID-19, it is nevertheless useful because of equipment portability, low cost and practicality in serial assessments of disease progression among hospitalized patients. Objective: This study aims to review the typical and relatively atypical CXR manifestations of COVID-19 pneumonia in a tertiary care hospital. Methods: The CXRs of 136 COVID-19 patients confirmed through real-time RT-PCR from March to May 2020 were reviewed. A literature search was performed using PubMed. Results: A total of 54 patients had abnormal CXR whilst the others were normal. Typical CXR findings included pulmonary consolidation or ground-glass opacities in a multifocal, bilateral pe-ripheral, or lower zone distribution, whereas atypical CXR features comprised cavitation and pleu-ral effusion. Conclusion: Typical findings of COVID-19 infection in chest computed tomography studies can also be seen in CXR. The presence of atypical features associated with worse disease outcome. Recognition of these features on CXR will improve the accuracy and speed of diagnosing COVID-19 patients. © 2021 Bentham Science Publishers.
format Article
author Chan, Wai Yee
Hamid, Marlina Tanty Ramli
Gowdh, Nadia Fareeda Muhammad
Rahmat, Kartini
Yaakup, Nur Adura
Chai, Chee Shee
author_facet Chan, Wai Yee
Hamid, Marlina Tanty Ramli
Gowdh, Nadia Fareeda Muhammad
Rahmat, Kartini
Yaakup, Nur Adura
Chai, Chee Shee
author_sort Chan, Wai Yee
title Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
title_short Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
title_full Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
title_fullStr Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
title_full_unstemmed Chest radiograph (CXR) manifestations of the novel coronavirus sisease 2019 (COVID-19): A mini-review
title_sort chest radiograph (cxr) manifestations of the novel coronavirus sisease 2019 (covid-19): a mini-review
publisher Bentham Science Publ Ltd
publishDate 2021
url http://eprints.um.edu.my/35462/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112124816&doi=10.2174%2f1573405616666201231103312&partnerID=40&md5=6f83f6f978542556b18675dd83e6cad6
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score 13.211869