Staff View: The case for simplifying and using absolute targets for viral hepatitis elimination goals

The case for simplifying and using absolute targets for viral hepatitis elimination goals

The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis...

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Main Authors:	Razavi, Homie, Blach, Sarah, Razavi-Shearers, Devin, Abaalkhail, Faisal, Abbas, Zaigham, Abdallah, Ayat, Ferreira, Paulo Abrao, Abu Raddad, Laith Jamal, Adda, Danjuma, Agarwal, Kosh, Aghemo, Alessio, Ahmed, Aijaz, Al-Busafi, Said A., Al-hamoudi, Waleed, Al-Kaabi, Saad, Al-Romaihi, Hamad, Aljarallah, Badr, AlNaamani, Khalid, Alqahtani, Saleh, Alswat, Khalid, Altraif, Ibrahim, Asselah, Tarik, Bacon, Bruce, Bessone, Fernando, Bizri, Abdul Rahman, Block, Tim, Bonino, Ferruccio, BranclaoMello, Carlos Eduardo, Browny, Kimberly, Bruggmann, Philip, Brunetto, Maurizia Rossana, Buti, Maria, Cabezas, Joaquin, Calleja, Jose Luis, Batanjer, Erika Castro, Chan, Henry Lik-Yuen, Chang, Henry, Chen, Chien-Jen, Christensen, Peer Brehm, Chuang, Wan-Long, Cisneros, Laura, Cohen, Chari, Colombo, Massimo, Conway, Brian, Cooper, Curtis, Craxi, Antonio, Crespo, Javier, Croes, Esther, Cryer, Donna, de Barros, Fernando Passos Cupertino, Derbala, Moutaz, Dillon, John, Doss, Wahid, Dou, Xiaoguang, Doyle, Joseph, Duberg, Ann-Sofi, Dugan, Ellen, Dunn, Rick, Dusheiko, Geoffrey, El Khayat, Hisham, EI-Sayed, Manal H., Eshraghian, Ahad, Esmat, Gamal, Mur, Rafael Esteban, Ezzat, Sameera, Falconer, Karolin, Fassio, Eduardo, Ferrinho, Paulo, Flamm, Steven, Flisiak, Robert, Foster, Graham, Fung, James, Garcia-Samaniego, Javier, Gish, Robert G., Goncales, Fernando, Halota, Waldemar, Hamoudi, Waseem, Hassany, Mohamed, Hatzakis, Angelos, Hay, Susan, Himatt, Sayed, Hoepelman, I. M., Hsu, Yao-Chun, Hui, Yee Tak, Hunyady, Bela, Jacobson, Ira, Janjua, Naveed, Janssen, Harry, Jarcuska, Peter, Kabagambe, Kenneth, Kanto, Tatsuya, Kao, Jia-Horng, Kaymakoglu, Sabahattin, Kershenobich, David, Khamis, Faryal, Kim, Dong Joon, Kim, Young, Kondili, Loreta A., KottiliI, Shyamasundaran, Kramvis, Anna, Kugelmas, Marcelo, Kurosaki, Masayuki, Lacombe, Karine, Lagging, Martin, Lao, WaiCheung, Lavanchy, Daniel, Lazarus, Jeffrey, Lee, Alice, Lee, Samual S., Levyl, Miriam, Liakina, Valentina, Lim, YoungSuk, Liu, Shuang, Maddrey, Willis, Malekzade, Reza, Marinho, Rui Tato, Mathur, Poonam, Maticic, Mojca, Mendes Correa, Maria Cassia, Mera, Jorge, Merat, Shahin, Mogawer, Sherif, Mohamed, Rosmawati, Muellhaupti, Beat, Muljono, David, Mostafa, Ibrahim, Nahum, Mendez Sanchez, Nawaz, Arif, Negro, Francesco, Ninburg, Michael, Ning, Qing, Ntiri-Reid, Boatemaa, Nymadawa, Pagbajabyn, Oevrehus, Anne, Ormeci, Necati, Orrego, Mauricio, Osman, Alaa, Oyunsuren, Tsendsuren, Pant, Calvin, Papaevangelou, Vassiliki, Papatheodoridis, George, Popping, Stephanie, Prasad, Papu, Prithiviputh, Rittoo, Qureshi, Huma, Ramji, Alnoor, Razavi-Shearer, Kathryn, Reddy, Rajender, Remak, William, Richter, Clemens, Ridruejo, Ezequiel, Robaeys, Geert, Robert, Stuart, Roberts, Lewis, Roudot-Thoraval, Francoise, Saab, Sammy, Said, Sanaa, Salamat, Amjad, Sanai, Faisal, Sanchez-Avila, Juan Francisco, Schiff, Eugene, Schinazi, Raymond, Sebastiani, Giada, Seguin-Devaux, Carole, Shanmugam, R. P., Sharara, Ala, Shilton, Sonjelle, Shouval, Daniel, Sievert, William, Simonova, Marieta, Sohrabpour, Amir Ali, Sonderup, Mark, Soza, Alejandro, Spearman, C. Wendy, Steinfurth, Nancy, Sulkowski, Mark, Tan, Soek-Siam, Tanaka, Junko, Tashi, Dhondup, Thein, Hla-Hla, Thompson, Peyton, Tolmane, Ieva, Toy, Mehlika, Valantinas, Jonas, Van de Vijver, David, Velez-Moller, Patricia, Vince, Adriana, Waked, Imam, Wang, Su, Wedemeyer, Heiner, Wong, Vincent, Xie, Qing, Yamada, Seiji, Yang, Hwai-, Yesmembetov, Kakharman, Yilmaz, Yusuf, Younossi, Zobair, Yu, Ming-Lung, Yuen, Man-Fung, Yurdaydin, Cihan, Yusuf, Aasim, Zekry, Amany, Zeuzem, Stefan
Format:	Article
Published:	Wiley 2021
Subjects:	QR Microbiology QR355 Virology R Medicine RB Pathology Theories of disease. Etiology. Pathogenesis
Online Access:	http://eprints.um.edu.my/34732/
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url_provider	http://eprints.um.edu.my/
topic	QR Microbiology QR355 Virology R Medicine RB Pathology Theories of disease. Etiology. Pathogenesis
spellingShingle	QR Microbiology QR355 Virology R Medicine RB Pathology Theories of disease. Etiology. Pathogenesis Razavi, Homie Blach, Sarah Razavi-Shearers, Devin Abaalkhail, Faisal Abbas, Zaigham Abdallah, Ayat Ferreira, Paulo Abrao Abu Raddad, Laith Jamal Adda, Danjuma Agarwal, Kosh Aghemo, Alessio Ahmed, Aijaz Al-Busafi, Said A. Al-hamoudi, Waleed Al-Kaabi, Saad Al-Romaihi, Hamad Aljarallah, Badr AlNaamani, Khalid Alqahtani, Saleh Alswat, Khalid Altraif, Ibrahim Asselah, Tarik Bacon, Bruce Bessone, Fernando Bizri, Abdul Rahman Block, Tim Bonino, Ferruccio BranclaoMello, Carlos Eduardo Browny, Kimberly Bruggmann, Philip Brunetto, Maurizia Rossana Buti, Maria Cabezas, Joaquin Calleja, Jose Luis Batanjer, Erika Castro Chan, Henry Lik-Yuen Chang, Henry Chen, Chien-Jen Christensen, Peer Brehm Chuang, Wan-Long Cisneros, Laura Cohen, Chari Colombo, Massimo Conway, Brian Cooper, Curtis Craxi, Antonio Crespo, Javier Croes, Esther Cryer, Donna de Barros, Fernando Passos Cupertino Derbala, Moutaz Dillon, John Doss, Wahid Dou, Xiaoguang Doyle, Joseph Duberg, Ann-Sofi Dugan, Ellen Dunn, Rick Dusheiko, Geoffrey El Khayat, Hisham EI-Sayed, Manal H. Eshraghian, Ahad Esmat, Gamal Mur, Rafael Esteban Ezzat, Sameera Falconer, Karolin Fassio, Eduardo Ferrinho, Paulo Flamm, Steven Flisiak, Robert Foster, Graham Fung, James Garcia-Samaniego, Javier Gish, Robert G. Goncales, Fernando Halota, Waldemar Hamoudi, Waseem Hassany, Mohamed Hatzakis, Angelos Hay, Susan Himatt, Sayed Hoepelman, I. M. Hsu, Yao-Chun Hui, Yee Tak Hunyady, Bela Jacobson, Ira Janjua, Naveed Janssen, Harry Jarcuska, Peter Kabagambe, Kenneth Kanto, Tatsuya Kao, Jia-Horng Kaymakoglu, Sabahattin Kershenobich, David Khamis, Faryal Kim, Dong Joon Kim, Young Kondili, Loreta A. KottiliI, Shyamasundaran Kramvis, Anna Kugelmas, Marcelo Kurosaki, Masayuki Lacombe, Karine Lagging, Martin Lao, WaiCheung Lavanchy, Daniel Lazarus, Jeffrey Lee, Alice Lee, Samual S. Levyl, Miriam Liakina, Valentina Lim, YoungSuk Liu, Shuang Maddrey, Willis Malekzade, Reza Marinho, Rui Tato Mathur, Poonam Maticic, Mojca Mendes Correa, Maria Cassia Mera, Jorge Merat, Shahin Mogawer, Sherif Mohamed, Rosmawati Muellhaupti, Beat Muljono, David Mostafa, Ibrahim Nahum, Mendez Sanchez Nawaz, Arif Negro, Francesco Ninburg, Michael Ning, Qing Ntiri-Reid, Boatemaa Nymadawa, Pagbajabyn Oevrehus, Anne Ormeci, Necati Orrego, Mauricio Osman, Alaa Oyunsuren, Tsendsuren Pant, Calvin Papaevangelou, Vassiliki Papatheodoridis, George Popping, Stephanie Prasad, Papu Prithiviputh, Rittoo Qureshi, Huma Ramji, Alnoor Razavi-Shearer, Kathryn Reddy, Rajender Remak, William Richter, Clemens Ridruejo, Ezequiel Robaeys, Geert Robert, Stuart Roberts, Lewis Roudot-Thoraval, Francoise Saab, Sammy Said, Sanaa Salamat, Amjad Sanai, Faisal Sanchez-Avila, Juan Francisco Schiff, Eugene Schinazi, Raymond Sebastiani, Giada Seguin-Devaux, Carole Shanmugam, R. P. Sharara, Ala Shilton, Sonjelle Shouval, Daniel Sievert, William Simonova, Marieta Sohrabpour, Amir Ali Sonderup, Mark Soza, Alejandro Spearman, C. Wendy Steinfurth, Nancy Sulkowski, Mark Tan, Soek-Siam Tanaka, Junko Tashi, Dhondup Thein, Hla-Hla Thompson, Peyton Tolmane, Ieva Toy, Mehlika Valantinas, Jonas Van de Vijver, David Velez-Moller, Patricia Vince, Adriana Waked, Imam Wang, Su Wedemeyer, Heiner Wong, Vincent Xie, Qing Yamada, Seiji Yang, Hwai- Yesmembetov, Kakharman Yilmaz, Yusuf Younossi, Zobair Yu, Ming-Lung Yuen, Man-Fung Yurdaydin, Cihan Yusuf, Aasim Zekry, Amany Zeuzem, Stefan The case for simplifying and using absolute targets for viral hepatitis elimination goals
description	The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries' progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to <= 5 per 100 000, reduce HBV prevalence among 1-year-olds to <= 0.1%, reduce HBV and HCV mortality to <= 5 per 100 000, and demonstrate HBV and HCV year-to-year decrease in new HCV- and HBV-related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.
format	Article
author	Razavi, Homie Blach, Sarah Razavi-Shearers, Devin Abaalkhail, Faisal Abbas, Zaigham Abdallah, Ayat Ferreira, Paulo Abrao Abu Raddad, Laith Jamal Adda, Danjuma Agarwal, Kosh Aghemo, Alessio Ahmed, Aijaz Al-Busafi, Said A. Al-hamoudi, Waleed Al-Kaabi, Saad Al-Romaihi, Hamad Aljarallah, Badr AlNaamani, Khalid Alqahtani, Saleh Alswat, Khalid Altraif, Ibrahim Asselah, Tarik Bacon, Bruce Bessone, Fernando Bizri, Abdul Rahman Block, Tim Bonino, Ferruccio BranclaoMello, Carlos Eduardo Browny, Kimberly Bruggmann, Philip Brunetto, Maurizia Rossana Buti, Maria Cabezas, Joaquin Calleja, Jose Luis Batanjer, Erika Castro Chan, Henry Lik-Yuen Chang, Henry Chen, Chien-Jen Christensen, Peer Brehm Chuang, Wan-Long Cisneros, Laura Cohen, Chari Colombo, Massimo Conway, Brian Cooper, Curtis Craxi, Antonio Crespo, Javier Croes, Esther Cryer, Donna de Barros, Fernando Passos Cupertino Derbala, Moutaz Dillon, John Doss, Wahid Dou, Xiaoguang Doyle, Joseph Duberg, Ann-Sofi Dugan, Ellen Dunn, Rick Dusheiko, Geoffrey El Khayat, Hisham EI-Sayed, Manal H. Eshraghian, Ahad Esmat, Gamal Mur, Rafael Esteban Ezzat, Sameera Falconer, Karolin Fassio, Eduardo Ferrinho, Paulo Flamm, Steven Flisiak, Robert Foster, Graham Fung, James Garcia-Samaniego, Javier Gish, Robert G. Goncales, Fernando Halota, Waldemar Hamoudi, Waseem Hassany, Mohamed Hatzakis, Angelos Hay, Susan Himatt, Sayed Hoepelman, I. M. Hsu, Yao-Chun Hui, Yee Tak Hunyady, Bela Jacobson, Ira Janjua, Naveed Janssen, Harry Jarcuska, Peter Kabagambe, Kenneth Kanto, Tatsuya Kao, Jia-Horng Kaymakoglu, Sabahattin Kershenobich, David Khamis, Faryal Kim, Dong Joon Kim, Young Kondili, Loreta A. KottiliI, Shyamasundaran Kramvis, Anna Kugelmas, Marcelo Kurosaki, Masayuki Lacombe, Karine Lagging, Martin Lao, WaiCheung Lavanchy, Daniel Lazarus, Jeffrey Lee, Alice Lee, Samual S. Levyl, Miriam Liakina, Valentina Lim, YoungSuk Liu, Shuang Maddrey, Willis Malekzade, Reza Marinho, Rui Tato Mathur, Poonam Maticic, Mojca Mendes Correa, Maria Cassia Mera, Jorge Merat, Shahin Mogawer, Sherif Mohamed, Rosmawati Muellhaupti, Beat Muljono, David Mostafa, Ibrahim Nahum, Mendez Sanchez Nawaz, Arif Negro, Francesco Ninburg, Michael Ning, Qing Ntiri-Reid, Boatemaa Nymadawa, Pagbajabyn Oevrehus, Anne Ormeci, Necati Orrego, Mauricio Osman, Alaa Oyunsuren, Tsendsuren Pant, Calvin Papaevangelou, Vassiliki Papatheodoridis, George Popping, Stephanie Prasad, Papu Prithiviputh, Rittoo Qureshi, Huma Ramji, Alnoor Razavi-Shearer, Kathryn Reddy, Rajender Remak, William Richter, Clemens Ridruejo, Ezequiel Robaeys, Geert Robert, Stuart Roberts, Lewis Roudot-Thoraval, Francoise Saab, Sammy Said, Sanaa Salamat, Amjad Sanai, Faisal Sanchez-Avila, Juan Francisco Schiff, Eugene Schinazi, Raymond Sebastiani, Giada Seguin-Devaux, Carole Shanmugam, R. P. Sharara, Ala Shilton, Sonjelle Shouval, Daniel Sievert, William Simonova, Marieta Sohrabpour, Amir Ali Sonderup, Mark Soza, Alejandro Spearman, C. Wendy Steinfurth, Nancy Sulkowski, Mark Tan, Soek-Siam Tanaka, Junko Tashi, Dhondup Thein, Hla-Hla Thompson, Peyton Tolmane, Ieva Toy, Mehlika Valantinas, Jonas Van de Vijver, David Velez-Moller, Patricia Vince, Adriana Waked, Imam Wang, Su Wedemeyer, Heiner Wong, Vincent Xie, Qing Yamada, Seiji Yang, Hwai- Yesmembetov, Kakharman Yilmaz, Yusuf Younossi, Zobair Yu, Ming-Lung Yuen, Man-Fung Yurdaydin, Cihan Yusuf, Aasim Zekry, Amany Zeuzem, Stefan
author_facet	Razavi, Homie Blach, Sarah Razavi-Shearers, Devin Abaalkhail, Faisal Abbas, Zaigham Abdallah, Ayat Ferreira, Paulo Abrao Abu Raddad, Laith Jamal Adda, Danjuma Agarwal, Kosh Aghemo, Alessio Ahmed, Aijaz Al-Busafi, Said A. Al-hamoudi, Waleed Al-Kaabi, Saad Al-Romaihi, Hamad Aljarallah, Badr AlNaamani, Khalid Alqahtani, Saleh Alswat, Khalid Altraif, Ibrahim Asselah, Tarik Bacon, Bruce Bessone, Fernando Bizri, Abdul Rahman Block, Tim Bonino, Ferruccio BranclaoMello, Carlos Eduardo Browny, Kimberly Bruggmann, Philip Brunetto, Maurizia Rossana Buti, Maria Cabezas, Joaquin Calleja, Jose Luis Batanjer, Erika Castro Chan, Henry Lik-Yuen Chang, Henry Chen, Chien-Jen Christensen, Peer Brehm Chuang, Wan-Long Cisneros, Laura Cohen, Chari Colombo, Massimo Conway, Brian Cooper, Curtis Craxi, Antonio Crespo, Javier Croes, Esther Cryer, Donna de Barros, Fernando Passos Cupertino Derbala, Moutaz Dillon, John Doss, Wahid Dou, Xiaoguang Doyle, Joseph Duberg, Ann-Sofi Dugan, Ellen Dunn, Rick Dusheiko, Geoffrey El Khayat, Hisham EI-Sayed, Manal H. Eshraghian, Ahad Esmat, Gamal Mur, Rafael Esteban Ezzat, Sameera Falconer, Karolin Fassio, Eduardo Ferrinho, Paulo Flamm, Steven Flisiak, Robert Foster, Graham Fung, James Garcia-Samaniego, Javier Gish, Robert G. Goncales, Fernando Halota, Waldemar Hamoudi, Waseem Hassany, Mohamed Hatzakis, Angelos Hay, Susan Himatt, Sayed Hoepelman, I. M. Hsu, Yao-Chun Hui, Yee Tak Hunyady, Bela Jacobson, Ira Janjua, Naveed Janssen, Harry Jarcuska, Peter Kabagambe, Kenneth Kanto, Tatsuya Kao, Jia-Horng Kaymakoglu, Sabahattin Kershenobich, David Khamis, Faryal Kim, Dong Joon Kim, Young Kondili, Loreta A. KottiliI, Shyamasundaran Kramvis, Anna Kugelmas, Marcelo Kurosaki, Masayuki Lacombe, Karine Lagging, Martin Lao, WaiCheung Lavanchy, Daniel Lazarus, Jeffrey Lee, Alice Lee, Samual S. Levyl, Miriam Liakina, Valentina Lim, YoungSuk Liu, Shuang Maddrey, Willis Malekzade, Reza Marinho, Rui Tato Mathur, Poonam Maticic, Mojca Mendes Correa, Maria Cassia Mera, Jorge Merat, Shahin Mogawer, Sherif Mohamed, Rosmawati Muellhaupti, Beat Muljono, David Mostafa, Ibrahim Nahum, Mendez Sanchez Nawaz, Arif Negro, Francesco Ninburg, Michael Ning, Qing Ntiri-Reid, Boatemaa Nymadawa, Pagbajabyn Oevrehus, Anne Ormeci, Necati Orrego, Mauricio Osman, Alaa Oyunsuren, Tsendsuren Pant, Calvin Papaevangelou, Vassiliki Papatheodoridis, George Popping, Stephanie Prasad, Papu Prithiviputh, Rittoo Qureshi, Huma Ramji, Alnoor Razavi-Shearer, Kathryn Reddy, Rajender Remak, William Richter, Clemens Ridruejo, Ezequiel Robaeys, Geert Robert, Stuart Roberts, Lewis Roudot-Thoraval, Francoise Saab, Sammy Said, Sanaa Salamat, Amjad Sanai, Faisal Sanchez-Avila, Juan Francisco Schiff, Eugene Schinazi, Raymond Sebastiani, Giada Seguin-Devaux, Carole Shanmugam, R. P. Sharara, Ala Shilton, Sonjelle Shouval, Daniel Sievert, William Simonova, Marieta Sohrabpour, Amir Ali Sonderup, Mark Soza, Alejandro Spearman, C. Wendy Steinfurth, Nancy Sulkowski, Mark Tan, Soek-Siam Tanaka, Junko Tashi, Dhondup Thein, Hla-Hla Thompson, Peyton Tolmane, Ieva Toy, Mehlika Valantinas, Jonas Van de Vijver, David Velez-Moller, Patricia Vince, Adriana Waked, Imam Wang, Su Wedemeyer, Heiner Wong, Vincent Xie, Qing Yamada, Seiji Yang, Hwai- Yesmembetov, Kakharman Yilmaz, Yusuf Younossi, Zobair Yu, Ming-Lung Yuen, Man-Fung Yurdaydin, Cihan Yusuf, Aasim Zekry, Amany Zeuzem, Stefan
author_sort	Razavi, Homie
title	The case for simplifying and using absolute targets for viral hepatitis elimination goals
title_short	The case for simplifying and using absolute targets for viral hepatitis elimination goals
title_full	The case for simplifying and using absolute targets for viral hepatitis elimination goals
title_fullStr	The case for simplifying and using absolute targets for viral hepatitis elimination goals
title_full_unstemmed	The case for simplifying and using absolute targets for viral hepatitis elimination goals
title_sort	case for simplifying and using absolute targets for viral hepatitis elimination goals
publisher	Wiley
publishDate	2021
url	http://eprints.um.edu.my/34732/
_version_	1744649196623888384
spelling	my.um.eprints.347322022-09-19T02:34:43Z http://eprints.um.edu.my/34732/ The case for simplifying and using absolute targets for viral hepatitis elimination goals Razavi, Homie Blach, Sarah Razavi-Shearers, Devin Abaalkhail, Faisal Abbas, Zaigham Abdallah, Ayat Ferreira, Paulo Abrao Abu Raddad, Laith Jamal Adda, Danjuma Agarwal, Kosh Aghemo, Alessio Ahmed, Aijaz Al-Busafi, Said A. Al-hamoudi, Waleed Al-Kaabi, Saad Al-Romaihi, Hamad Aljarallah, Badr AlNaamani, Khalid Alqahtani, Saleh Alswat, Khalid Altraif, Ibrahim Asselah, Tarik Bacon, Bruce Bessone, Fernando Bizri, Abdul Rahman Block, Tim Bonino, Ferruccio BranclaoMello, Carlos Eduardo Browny, Kimberly Bruggmann, Philip Brunetto, Maurizia Rossana Buti, Maria Cabezas, Joaquin Calleja, Jose Luis Batanjer, Erika Castro Chan, Henry Lik-Yuen Chang, Henry Chen, Chien-Jen Christensen, Peer Brehm Chuang, Wan-Long Cisneros, Laura Cohen, Chari Colombo, Massimo Conway, Brian Cooper, Curtis Craxi, Antonio Crespo, Javier Croes, Esther Cryer, Donna de Barros, Fernando Passos Cupertino Derbala, Moutaz Dillon, John Doss, Wahid Dou, Xiaoguang Doyle, Joseph Duberg, Ann-Sofi Dugan, Ellen Dunn, Rick Dusheiko, Geoffrey El Khayat, Hisham EI-Sayed, Manal H. Eshraghian, Ahad Esmat, Gamal Mur, Rafael Esteban Ezzat, Sameera Falconer, Karolin Fassio, Eduardo Ferrinho, Paulo Flamm, Steven Flisiak, Robert Foster, Graham Fung, James Garcia-Samaniego, Javier Gish, Robert G. Goncales, Fernando Halota, Waldemar Hamoudi, Waseem Hassany, Mohamed Hatzakis, Angelos Hay, Susan Himatt, Sayed Hoepelman, I. M. Hsu, Yao-Chun Hui, Yee Tak Hunyady, Bela Jacobson, Ira Janjua, Naveed Janssen, Harry Jarcuska, Peter Kabagambe, Kenneth Kanto, Tatsuya Kao, Jia-Horng Kaymakoglu, Sabahattin Kershenobich, David Khamis, Faryal Kim, Dong Joon Kim, Young Kondili, Loreta A. KottiliI, Shyamasundaran Kramvis, Anna Kugelmas, Marcelo Kurosaki, Masayuki Lacombe, Karine Lagging, Martin Lao, WaiCheung Lavanchy, Daniel Lazarus, Jeffrey Lee, Alice Lee, Samual S. Levyl, Miriam Liakina, Valentina Lim, YoungSuk Liu, Shuang Maddrey, Willis Malekzade, Reza Marinho, Rui Tato Mathur, Poonam Maticic, Mojca Mendes Correa, Maria Cassia Mera, Jorge Merat, Shahin Mogawer, Sherif Mohamed, Rosmawati Muellhaupti, Beat Muljono, David Mostafa, Ibrahim Nahum, Mendez Sanchez Nawaz, Arif Negro, Francesco Ninburg, Michael Ning, Qing Ntiri-Reid, Boatemaa Nymadawa, Pagbajabyn Oevrehus, Anne Ormeci, Necati Orrego, Mauricio Osman, Alaa Oyunsuren, Tsendsuren Pant, Calvin Papaevangelou, Vassiliki Papatheodoridis, George Popping, Stephanie Prasad, Papu Prithiviputh, Rittoo Qureshi, Huma Ramji, Alnoor Razavi-Shearer, Kathryn Reddy, Rajender Remak, William Richter, Clemens Ridruejo, Ezequiel Robaeys, Geert Robert, Stuart Roberts, Lewis Roudot-Thoraval, Francoise Saab, Sammy Said, Sanaa Salamat, Amjad Sanai, Faisal Sanchez-Avila, Juan Francisco Schiff, Eugene Schinazi, Raymond Sebastiani, Giada Seguin-Devaux, Carole Shanmugam, R. P. Sharara, Ala Shilton, Sonjelle Shouval, Daniel Sievert, William Simonova, Marieta Sohrabpour, Amir Ali Sonderup, Mark Soza, Alejandro Spearman, C. Wendy Steinfurth, Nancy Sulkowski, Mark Tan, Soek-Siam Tanaka, Junko Tashi, Dhondup Thein, Hla-Hla Thompson, Peyton Tolmane, Ieva Toy, Mehlika Valantinas, Jonas Van de Vijver, David Velez-Moller, Patricia Vince, Adriana Waked, Imam Wang, Su Wedemeyer, Heiner Wong, Vincent Xie, Qing Yamada, Seiji Yang, Hwai- Yesmembetov, Kakharman Yilmaz, Yusuf Younossi, Zobair Yu, Ming-Lung Yuen, Man-Fung Yurdaydin, Cihan Yusuf, Aasim Zekry, Amany Zeuzem, Stefan QR Microbiology QR355 Virology R Medicine RB Pathology Theories of disease. Etiology. Pathogenesis The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries' progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to <= 5 per 100 000, reduce HBV prevalence among 1-year-olds to <= 0.1%, reduce HBV and HCV mortality to <= 5 per 100 000, and demonstrate HBV and HCV year-to-year decrease in new HCV- and HBV-related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit. Wiley 2021-01 Article PeerReviewed Razavi, Homie and Blach, Sarah and Razavi-Shearers, Devin and Abaalkhail, Faisal and Abbas, Zaigham and Abdallah, Ayat and Ferreira, Paulo Abrao and Abu Raddad, Laith Jamal and Adda, Danjuma and Agarwal, Kosh and Aghemo, Alessio and Ahmed, Aijaz and Al-Busafi, Said A. and Al-hamoudi, Waleed and Al-Kaabi, Saad and Al-Romaihi, Hamad and Aljarallah, Badr and AlNaamani, Khalid and Alqahtani, Saleh and Alswat, Khalid and Altraif, Ibrahim and Asselah, Tarik and Bacon, Bruce and Bessone, Fernando and Bizri, Abdul Rahman and Block, Tim and Bonino, Ferruccio and BranclaoMello, Carlos Eduardo and Browny, Kimberly and Bruggmann, Philip and Brunetto, Maurizia Rossana and Buti, Maria and Cabezas, Joaquin and Calleja, Jose Luis and Batanjer, Erika Castro and Chan, Henry Lik-Yuen and Chang, Henry and Chen, Chien-Jen and Christensen, Peer Brehm and Chuang, Wan-Long and Cisneros, Laura and Cohen, Chari and Colombo, Massimo and Conway, Brian and Cooper, Curtis and Craxi, Antonio and Crespo, Javier and Croes, Esther and Cryer, Donna and de Barros, Fernando Passos Cupertino and Derbala, Moutaz and Dillon, John and Doss, Wahid and Dou, Xiaoguang and Doyle, Joseph and Duberg, Ann-Sofi and Dugan, Ellen and Dunn, Rick and Dusheiko, Geoffrey and El Khayat, Hisham and EI-Sayed, Manal H. and Eshraghian, Ahad and Esmat, Gamal and Mur, Rafael Esteban and Ezzat, Sameera and Falconer, Karolin and Fassio, Eduardo and Ferrinho, Paulo and Flamm, Steven and Flisiak, Robert and Foster, Graham and Fung, James and Garcia-Samaniego, Javier and Gish, Robert G. and Goncales, Fernando and Halota, Waldemar and Hamoudi, Waseem and Hassany, Mohamed and Hatzakis, Angelos and Hay, Susan and Himatt, Sayed and Hoepelman, I. M. and Hsu, Yao-Chun and Hui, Yee Tak and Hunyady, Bela and Jacobson, Ira and Janjua, Naveed and Janssen, Harry and Jarcuska, Peter and Kabagambe, Kenneth and Kanto, Tatsuya and Kao, Jia-Horng and Kaymakoglu, Sabahattin and Kershenobich, David and Khamis, Faryal and Kim, Dong Joon and Kim, Young and Kondili, Loreta A. and KottiliI, Shyamasundaran and Kramvis, Anna and Kugelmas, Marcelo and Kurosaki, Masayuki and Lacombe, Karine and Lagging, Martin and Lao, WaiCheung and Lavanchy, Daniel and Lazarus, Jeffrey and Lee, Alice and Lee, Samual S. and Levyl, Miriam and Liakina, Valentina and Lim, YoungSuk and Liu, Shuang and Maddrey, Willis and Malekzade, Reza and Marinho, Rui Tato and Mathur, Poonam and Maticic, Mojca and Mendes Correa, Maria Cassia and Mera, Jorge and Merat, Shahin and Mogawer, Sherif and Mohamed, Rosmawati and Muellhaupti, Beat and Muljono, David and Mostafa, Ibrahim and Nahum, Mendez Sanchez and Nawaz, Arif and Negro, Francesco and Ninburg, Michael and Ning, Qing and Ntiri-Reid, Boatemaa and Nymadawa, Pagbajabyn and Oevrehus, Anne and Ormeci, Necati and Orrego, Mauricio and Osman, Alaa and Oyunsuren, Tsendsuren and Pant, Calvin and Papaevangelou, Vassiliki and Papatheodoridis, George and Popping, Stephanie and Prasad, Papu and Prithiviputh, Rittoo and Qureshi, Huma and Ramji, Alnoor and Razavi-Shearer, Kathryn and Reddy, Rajender and Remak, William and Richter, Clemens and Ridruejo, Ezequiel and Robaeys, Geert and Robert, Stuart and Roberts, Lewis and Roudot-Thoraval, Francoise and Saab, Sammy and Said, Sanaa and Salamat, Amjad and Sanai, Faisal and Sanchez-Avila, Juan Francisco and Schiff, Eugene and Schinazi, Raymond and Sebastiani, Giada and Seguin-Devaux, Carole and Shanmugam, R. P. and Sharara, Ala and Shilton, Sonjelle and Shouval, Daniel and Sievert, William and Simonova, Marieta and Sohrabpour, Amir Ali and Sonderup, Mark and Soza, Alejandro and Spearman, C. Wendy and Steinfurth, Nancy and Sulkowski, Mark and Tan, Soek-Siam and Tanaka, Junko and Tashi, Dhondup and Thein, Hla-Hla and Thompson, Peyton and Tolmane, Ieva and Toy, Mehlika and Valantinas, Jonas and Van de Vijver, David and Velez-Moller, Patricia and Vince, Adriana and Waked, Imam and Wang, Su and Wedemeyer, Heiner and Wong, Vincent and Xie, Qing and Yamada, Seiji and Yang, Hwai- and Yesmembetov, Kakharman and Yilmaz, Yusuf and Younossi, Zobair and Yu, Ming-Lung and Yuen, Man-Fung and Yurdaydin, Cihan and Yusuf, Aasim and Zekry, Amany and Zeuzem, Stefan (2021) The case for simplifying and using absolute targets for viral hepatitis elimination goals. Journal of Viral Hepatitis, 28 (1). pp. 12-19. ISSN 1352-0504, DOI https://doi.org/10.1111/jvh.13412 <https://doi.org/10.1111/jvh.13412>. 10.1111/jvh.13412
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The case for simplifying and using absolute targets for viral hepatitis elimination goals

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