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Vaccines targeting novel cancer-associated antigens frequently expressed in head and neck cancer enhance the efficacy of checkpoint inhibitor

HPV-independent head and neck squamous cell carcinoma (HNSCC) is a common cancer globally. The overall response rate to anti-PD1 checkpoint inhibitors (CPIs) in HNSCC is similar to 16%. One major factor influencing the effectiveness of CPI is the level of tumor infiltrating T cells (TILs). Convertin...

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Bibliographic Details
Main Authors: Wang, Chuan, Zainal, Nur Syafinaz, Chai, San Jiun, Dickie, James, Gan, Chai Phei, Zulaziz, Natasha, Lye, Bryan Kit Weng, Sutavani, Ruhcha, Ottensmeier, Christian H., King, Emma, Abraham, Mannil Thomas, Ismail, Siti Mazlipah, Lau, Shin Hin, Kallarakkal, Thomas George, Mun, Kein Seong, Zain, Rosnah, Rahman, Zainal Ariff Abdul, Thomas, Gareth J., Cheong, Sok Ching, Savelyeva, Natalia, Lim, Kue Peng
Format: Article
Published: Frontiers Media 2021
Subjects:
QR180 Immunology
Online Access:http://eprints.um.edu.my/34676/
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