Staff View: Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity

Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity

The present study investigates deep eutectic solvents (DESs) as potential media for enzymatic hydrolysis. A series of ternary ammonium and phosphonium-based DESs were prepared at different molar ratios by mixing with aqueous glycerol (85%). The physicochemical properties including surface tension, c...

Full description

Saved in:

Bibliographic Details
Main Authors:	Rashid, Shahidah Nusailah, Hayyan, Adeeb, Hayyan, Maan, Hashim, Mohd Ali, Elgharbawy, Amal A. M., Sani, Fazrizatul Shakilla, Basirun, Wan Jefrey, Lee, Vannajan Sanghiran, Alias, Yatimah, Mohammed, Alaa Kareem, Mirghani, Mohamed E. S., Zulkifli, Mohd Yakub, Rageh, Maher
Format:	Article
Published:	Elsevier 2021
Subjects:	TA Engineering (General). Civil engineering (General)
Online Access:	http://eprints.um.edu.my/34556/
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.um.eprints.34556
record_format	eprints
spelling	my.um.eprints.345562022-09-14T08:06:58Z http://eprints.um.edu.my/34556/ Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity Rashid, Shahidah Nusailah Hayyan, Adeeb Hayyan, Maan Hashim, Mohd Ali Elgharbawy, Amal A. M. Sani, Fazrizatul Shakilla Basirun, Wan Jefrey Lee, Vannajan Sanghiran Alias, Yatimah Mohammed, Alaa Kareem Mirghani, Mohamed E. S. Zulkifli, Mohd Yakub Rageh, Maher TA Engineering (General). Civil engineering (General) The present study investigates deep eutectic solvents (DESs) as potential media for enzymatic hydrolysis. A series of ternary ammonium and phosphonium-based DESs were prepared at different molar ratios by mixing with aqueous glycerol (85%). The physicochemical properties including surface tension, conductivity, density, and viscosity were measured at a temperature range of 298.15 K - 363.15 K. The eutectic points were highly influenced by the variation of temperature. The eutectic point of the choline chloride: glycerol: water (ratio of 1: 2.55: 2.28) and methyltriphenylphosphonium bromide:glycerol:water (ratio of 1: 4.25: 3.75) is 213.4 K and 255.8 K, respectively. The stability of the lipase enzyme isolated from porcine pancreas (PPL) and Rhizopus niveus (RNL) toward hydrolysis in ternary DESs medium was investigated. The PPL showed higher activity compared to the RNL in DESs. Molecular docking simulation of the selected DES with the substrate (p-nitrophenyl palmitate) toward PPL was also reported. It is worth noting that ternary DES systems would be viable lipase activators in hydrolysis reactions. (c) 2021 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved. Elsevier 2021-05 Article PeerReviewed Rashid, Shahidah Nusailah and Hayyan, Adeeb and Hayyan, Maan and Hashim, Mohd Ali and Elgharbawy, Amal A. M. and Sani, Fazrizatul Shakilla and Basirun, Wan Jefrey and Lee, Vannajan Sanghiran and Alias, Yatimah and Mohammed, Alaa Kareem and Mirghani, Mohamed E. S. and Zulkifli, Mohd Yakub and Rageh, Maher (2021) Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity. Chemical Engineering Research & Design, 169. pp. 77-85. ISSN 0263-8762, DOI https://doi.org/10.1016/j.cherd.2021.02.032 <https://doi.org/10.1016/j.cherd.2021.02.032>. 10.1016/j.cherd.2021.02.032
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	TA Engineering (General). Civil engineering (General)
spellingShingle	TA Engineering (General). Civil engineering (General) Rashid, Shahidah Nusailah Hayyan, Adeeb Hayyan, Maan Hashim, Mohd Ali Elgharbawy, Amal A. M. Sani, Fazrizatul Shakilla Basirun, Wan Jefrey Lee, Vannajan Sanghiran Alias, Yatimah Mohammed, Alaa Kareem Mirghani, Mohamed E. S. Zulkifli, Mohd Yakub Rageh, Maher Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
description	The present study investigates deep eutectic solvents (DESs) as potential media for enzymatic hydrolysis. A series of ternary ammonium and phosphonium-based DESs were prepared at different molar ratios by mixing with aqueous glycerol (85%). The physicochemical properties including surface tension, conductivity, density, and viscosity were measured at a temperature range of 298.15 K - 363.15 K. The eutectic points were highly influenced by the variation of temperature. The eutectic point of the choline chloride: glycerol: water (ratio of 1: 2.55: 2.28) and methyltriphenylphosphonium bromide:glycerol:water (ratio of 1: 4.25: 3.75) is 213.4 K and 255.8 K, respectively. The stability of the lipase enzyme isolated from porcine pancreas (PPL) and Rhizopus niveus (RNL) toward hydrolysis in ternary DESs medium was investigated. The PPL showed higher activity compared to the RNL in DESs. Molecular docking simulation of the selected DES with the substrate (p-nitrophenyl palmitate) toward PPL was also reported. It is worth noting that ternary DES systems would be viable lipase activators in hydrolysis reactions. (c) 2021 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
format	Article
author	Rashid, Shahidah Nusailah Hayyan, Adeeb Hayyan, Maan Hashim, Mohd Ali Elgharbawy, Amal A. M. Sani, Fazrizatul Shakilla Basirun, Wan Jefrey Lee, Vannajan Sanghiran Alias, Yatimah Mohammed, Alaa Kareem Mirghani, Mohamed E. S. Zulkifli, Mohd Yakub Rageh, Maher
author_facet	Rashid, Shahidah Nusailah Hayyan, Adeeb Hayyan, Maan Hashim, Mohd Ali Elgharbawy, Amal A. M. Sani, Fazrizatul Shakilla Basirun, Wan Jefrey Lee, Vannajan Sanghiran Alias, Yatimah Mohammed, Alaa Kareem Mirghani, Mohamed E. S. Zulkifli, Mohd Yakub Rageh, Maher
author_sort	Rashid, Shahidah Nusailah
title	Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
title_short	Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
title_full	Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
title_fullStr	Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
title_full_unstemmed	Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity
title_sort	ternary glycerol-based deep eutectic solvents: physicochemical properties and enzymatic activity
publisher	Elsevier
publishDate	2021
url	http://eprints.um.edu.my/34556/
_version_	1744649186895200256
score	13.211869

Ternary glycerol-based deep eutectic solvents: Physicochemical properties and enzymatic activity

Similar Items