Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NF kappa B to promote axonal regeneration and remyelination
Epigenetic regulation by histone deacetylases (HDACs) in Schwann cells (SCs) after injury facilitates them to undergo de- and redifferentiation processes necessary to support various stages of nerve repair. Although de-differentiation activates the synthesis and secretion of inflammatory cytokines b...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
BMC
2021
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/34294/ |
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