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Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review

Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case Report: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and absce...

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Main Authors: Ab Mumin, Nazimah, Rahmat, Kartini, Hamid, Marlina Tanty Ramli, Ng, Wei Lin, Chan, Wai Yee, Cheah, Xin Ying, See, Mee Hoong, Yip, Cheng Har
Format: Article
Published: Bentham Science Publishers 2021
Subjects:
R Medicine (General)
T Technology (General)
Online Access:http://eprints.um.edu.my/34058/
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spelling my.um.eprints.340582022-06-20T07:31:48Z http://eprints.um.edu.my/34058/ Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review Ab Mumin, Nazimah Rahmat, Kartini Hamid, Marlina Tanty Ramli Ng, Wei Lin Chan, Wai Yee Cheah, Xin Ying See, Mee Hoong Yip, Cheng Har R Medicine (General) T Technology (General) Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case Report: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy. Discussion: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement. Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay. Bentham Science Publishers 2021 Article PeerReviewed Ab Mumin, Nazimah and Rahmat, Kartini and Hamid, Marlina Tanty Ramli and Ng, Wei Lin and Chan, Wai Yee and Cheah, Xin Ying and See, Mee Hoong and Yip, Cheng Har (2021) Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review. Current Medical Imaging, 17 (4). pp. 552-558. ISSN 1573-4056, DOI https://doi.org/10.2174/1573405616666201007161119 <https://doi.org/10.2174/1573405616666201007161119>. (In Press) 10.2174/1573405616666201007161119
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
T Technology (General)
spellingShingle R Medicine (General)
T Technology (General)
Ab Mumin, Nazimah
Rahmat, Kartini
Hamid, Marlina Tanty Ramli
Ng, Wei Lin
Chan, Wai Yee
Cheah, Xin Ying
See, Mee Hoong
Yip, Cheng Har
Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
description Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case Report: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy. Discussion: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement. Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.
format Article
author Ab Mumin, Nazimah
Rahmat, Kartini
Hamid, Marlina Tanty Ramli
Ng, Wei Lin
Chan, Wai Yee
Cheah, Xin Ying
See, Mee Hoong
Yip, Cheng Har
author_facet Ab Mumin, Nazimah
Rahmat, Kartini
Hamid, Marlina Tanty Ramli
Ng, Wei Lin
Chan, Wai Yee
Cheah, Xin Ying
See, Mee Hoong
Yip, Cheng Har
author_sort Ab Mumin, Nazimah
title Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
title_short Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
title_full Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
title_fullStr Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
title_full_unstemmed Primary breast angiosarcoma: Utilisation of pre-surgical magnetic resonance imaging (MRI) for accurate tumour characterization and planning - a case report and literature review
title_sort primary breast angiosarcoma: utilisation of pre-surgical magnetic resonance imaging (mri) for accurate tumour characterization and planning - a case report and literature review
publisher Bentham Science Publishers
publishDate 2021
url http://eprints.um.edu.my/34058/
_version_ 1738510706467143680
score 13.211869

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