Staff View: An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods

An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods

People spend a substantial proportion of their time indoors; therefore, exposure to contaminants in indoor dust is persistent and profuse. According to the findings of recent studies, contaminants such as flame retardants (FRs), organochlorines (OCs), and phthalate esters (PAEs) are more prevalent i...

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Main Authors:	Gunathilake, Thennakoon M. Sampath U., Ching, Yern Chee, Kadokami, Kiwao
Format:	Article
Published:	Springer 2022
Subjects:	TA Engineering (General). Civil engineering (General) TD Environmental technology. Sanitary engineering
Online Access:	http://eprints.um.edu.my/33814/
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spelling	my.um.eprints.338142022-04-25T06:59:29Z http://eprints.um.edu.my/33814/ An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods Gunathilake, Thennakoon M. Sampath U. Ching, Yern Chee Kadokami, Kiwao TA Engineering (General). Civil engineering (General) TD Environmental technology. Sanitary engineering People spend a substantial proportion of their time indoors; therefore, exposure to contaminants in indoor dust is persistent and profuse. According to the findings of recent studies, contaminants such as flame retardants (FRs), organochlorines (OCs), and phthalate esters (PAEs) are more prevalent in indoor dust. The discrepancy in the geographical distribution of these chemicals indicates country-specific applications. However, many studies have revealed that chlorophosphates, polychlorinated biphenyls (PCBs) and di-2-ethylhexyl phthalate are frequently detected in indoor dust throughout the world. Although some chemicals (e.g., OCs) were banned/severely restricted decades ago, they have still been detected in indoor dust. These organic contaminants have shown clear evidence of carcinogenic, neurotoxic, immunogenic, and estrogenic activities. Recent extraction methods have shown their advantages, such as high recoveries, less solvent consumption, less extraction time and simplicity of use. The latest separation techniques such as two-dimensional gas/liquid chromatography, latest ionization techniques (e.g., matrix-assisted laser desorption/ionization (MALDI)), and modern techniques of mass spectrometry (e.g., tandem mass spectrometry (MS/MS), time-of-flight (TOF) and high-resolution mass spectrometry (HRMS)) improve the detection limits, accuracy, reproducibility and simultaneous detection of organic contaminants. For future perspectives, it is suggested that the importance of the study of dust morphology for comprehensive risk analysis, introducing standard reference materials to strengthen the analytical methods, adopt common guidelines for comparison of research findings and the importance of dust analysis in the developing world since lack of records on the production and usage of hazardous substances. Such measures will help to evaluate the effectiveness of prevailing legislations and to set up new regulations. Springer 2022-03 Article PeerReviewed Gunathilake, Thennakoon M. Sampath U. and Ching, Yern Chee and Kadokami, Kiwao (2022) An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods. Environmental Geochemistry and Health, 44 (3). pp. 677-713. ISSN 0269-4042, DOI https://doi.org/10.1007/s10653-021-01013-x <https://doi.org/10.1007/s10653-021-01013-x>. 10.1007/s10653-021-01013-x
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	TA Engineering (General). Civil engineering (General) TD Environmental technology. Sanitary engineering
spellingShingle	TA Engineering (General). Civil engineering (General) TD Environmental technology. Sanitary engineering Gunathilake, Thennakoon M. Sampath U. Ching, Yern Chee Kadokami, Kiwao An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
description	People spend a substantial proportion of their time indoors; therefore, exposure to contaminants in indoor dust is persistent and profuse. According to the findings of recent studies, contaminants such as flame retardants (FRs), organochlorines (OCs), and phthalate esters (PAEs) are more prevalent in indoor dust. The discrepancy in the geographical distribution of these chemicals indicates country-specific applications. However, many studies have revealed that chlorophosphates, polychlorinated biphenyls (PCBs) and di-2-ethylhexyl phthalate are frequently detected in indoor dust throughout the world. Although some chemicals (e.g., OCs) were banned/severely restricted decades ago, they have still been detected in indoor dust. These organic contaminants have shown clear evidence of carcinogenic, neurotoxic, immunogenic, and estrogenic activities. Recent extraction methods have shown their advantages, such as high recoveries, less solvent consumption, less extraction time and simplicity of use. The latest separation techniques such as two-dimensional gas/liquid chromatography, latest ionization techniques (e.g., matrix-assisted laser desorption/ionization (MALDI)), and modern techniques of mass spectrometry (e.g., tandem mass spectrometry (MS/MS), time-of-flight (TOF) and high-resolution mass spectrometry (HRMS)) improve the detection limits, accuracy, reproducibility and simultaneous detection of organic contaminants. For future perspectives, it is suggested that the importance of the study of dust morphology for comprehensive risk analysis, introducing standard reference materials to strengthen the analytical methods, adopt common guidelines for comparison of research findings and the importance of dust analysis in the developing world since lack of records on the production and usage of hazardous substances. Such measures will help to evaluate the effectiveness of prevailing legislations and to set up new regulations.
format	Article
author	Gunathilake, Thennakoon M. Sampath U. Ching, Yern Chee Kadokami, Kiwao
author_facet	Gunathilake, Thennakoon M. Sampath U. Ching, Yern Chee Kadokami, Kiwao
author_sort	Gunathilake, Thennakoon M. Sampath U.
title	An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
title_short	An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
title_full	An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
title_fullStr	An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
title_full_unstemmed	An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
title_sort	overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods
publisher	Springer
publishDate	2022
url	http://eprints.um.edu.my/33814/
_version_	1735409594870530048
score	13.211869

An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods

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