Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide

Peripheral neuropathy is a known manifestation of systemic lupus erythematosus. However, the association of primary autoimmune inflammatory neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) with SLE is uncommon. We report a 26-year-old man who simultaneously presented wit...

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Main Authors: Jasmin, R., Sockalingam, S., Shahrizaila, N., Cheah, T.E., Zain, A., Goh, K.J.
Format: Article
Published: Arnold Publishers (journals now owned by Sage) 2012
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Online Access:http://eprints.um.edu.my/2973/
http://www.ncbi.nlm.nih.gov/pubmed/22433918
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spelling my.um.eprints.29732013-12-11T07:15:00Z http://eprints.um.edu.my/2973/ Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide Jasmin, R. Sockalingam, S. Shahrizaila, N. Cheah, T.E. Zain, A. Goh, K.J. R Medicine Peripheral neuropathy is a known manifestation of systemic lupus erythematosus. However, the association of primary autoimmune inflammatory neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) with SLE is uncommon. We report a 26-year-old man who simultaneously presented with severe CIDP and photosensitive rash, but was unresponsive to intravenous immunoglobulin infusion and continued to progress. He was found to have underlying SLE and improved with combined corticosteroid and immunosuppressive therapy with oral cyclophosphamide. CIDP with underlying SLE may be more resistant to conventional therapy with IVIG, requiring the addition of other immunosuppressive agents. Arnold Publishers (journals now owned by Sage) 2012-03 Article PeerReviewed Jasmin, R. and Sockalingam, S. and Shahrizaila, N. and Cheah, T.E. and Zain, A. and Goh, K.J. (2012) Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide. Lupus. ISSN 0961-2033 http://www.ncbi.nlm.nih.gov/pubmed/22433918 PMID: 22433918
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Jasmin, R.
Sockalingam, S.
Shahrizaila, N.
Cheah, T.E.
Zain, A.
Goh, K.J.
Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
description Peripheral neuropathy is a known manifestation of systemic lupus erythematosus. However, the association of primary autoimmune inflammatory neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) with SLE is uncommon. We report a 26-year-old man who simultaneously presented with severe CIDP and photosensitive rash, but was unresponsive to intravenous immunoglobulin infusion and continued to progress. He was found to have underlying SLE and improved with combined corticosteroid and immunosuppressive therapy with oral cyclophosphamide. CIDP with underlying SLE may be more resistant to conventional therapy with IVIG, requiring the addition of other immunosuppressive agents.
format Article
author Jasmin, R.
Sockalingam, S.
Shahrizaila, N.
Cheah, T.E.
Zain, A.
Goh, K.J.
author_facet Jasmin, R.
Sockalingam, S.
Shahrizaila, N.
Cheah, T.E.
Zain, A.
Goh, K.J.
author_sort Jasmin, R.
title Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
title_short Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
title_full Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
title_fullStr Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
title_full_unstemmed Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide
title_sort successful treatment of chronic inflammatory demyelinating polyneuropathy (cidp) in systemic lupus erythematosus (sle) with oral cyclophosphamide
publisher Arnold Publishers (journals now owned by Sage)
publishDate 2012
url http://eprints.um.edu.my/2973/
http://www.ncbi.nlm.nih.gov/pubmed/22433918
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