Staff View: The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels

The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels

Purpose The purpose of this study is to modify guar gum (GG) into guar gum acetate (GGA) and phthaloyl guar gum (PHGG) by transesterification and phthaloylation, respectively. Design/methodology/approach GG has been modified into GGA through transesterification reaction between GG and vinyl acetate...

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Main Authors:	Mazlan, Mazrina, Rizwan, Muhammad, Azzahari, Ahmad Danial, Selvanathan, Vidhya, Sonsudin, Faridah, Shahabudin, Nurshafiza
Format:	Article
Published:	Emerald 2021
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://eprints.um.edu.my/28541/
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spelling	my.um.eprints.285412022-08-16T07:56:38Z http://eprints.um.edu.my/28541/ The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels Mazlan, Mazrina Rizwan, Muhammad Azzahari, Ahmad Danial Selvanathan, Vidhya Sonsudin, Faridah Shahabudin, Nurshafiza Q Science (General) QD Chemistry Purpose The purpose of this study is to modify guar gum (GG) into guar gum acetate (GGA) and phthaloyl guar gum (PHGG) by transesterification and phthaloylation, respectively. Design/methodology/approach GG has been modified into GGA through transesterification reaction between GG and vinyl acetate and PHGG through esterification reaction with phthalic anhydride. The modified GG was characterized by solubility test, Fourier-transform infra-red (FTIR) spectroscopy, proton nuclear magnetic resonance (H-1 NMR) spectroscopy, X-ray diffractometry (XRD) and thermogravimetric analysis. Swelling properties of GGA and PHGG hydrogels in water were evaluated. Findings These two types of modified GG have better solubility such as in dimethyl sulfoxide and N,N-dimethylformamide but no true organosolubility was achieved. The modifications were confirmed through FTIR with new absorption peaks at 1,733 cm(-1) for GGA and 1,709 cm(-1) for PHGG coupled with observed substitution peaks at 1.80 to 2.20 ppm and 7.40 to 7.90 ppm, respectively, from H-1 NMR spectroscopies. XRD revealed both GGA and PHGG are less crystalline than native GG. GGA was found to be more thermally stable than native GG, whereas PHGG was slightly less thermally stable than native GG. The swelling property in distilled water for native GG, PHGG and GGA was 918.43 +/- 46.62%, 537.04 +/- 2.87% and 393.04 +/- 13.42%, respectively. Research limitations/implications The GGA and PHGG hydrogels are expected to be useful for biomedical fields such as tissue engineering and drug-delivery. Originality/value Modifications of native GG into GGA using vinyl acetate and PHGG using phthalic anhydride are novel. Emerald 2021-11-15 Article PeerReviewed Mazlan, Mazrina and Rizwan, Muhammad and Azzahari, Ahmad Danial and Selvanathan, Vidhya and Sonsudin, Faridah and Shahabudin, Nurshafiza (2021) The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels. Pigment & Resin Technology, 50 (6). pp. 485-495. ISSN 0369-9420, DOI https://doi.org/10.1108/PRT-06-2020-0063 <https://doi.org/10.1108/PRT-06-2020-0063>. 10.1108/PRT-06-2020-0063
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	Q Science (General) QD Chemistry
spellingShingle	Q Science (General) QD Chemistry Mazlan, Mazrina Rizwan, Muhammad Azzahari, Ahmad Danial Selvanathan, Vidhya Sonsudin, Faridah Shahabudin, Nurshafiza The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
description	Purpose The purpose of this study is to modify guar gum (GG) into guar gum acetate (GGA) and phthaloyl guar gum (PHGG) by transesterification and phthaloylation, respectively. Design/methodology/approach GG has been modified into GGA through transesterification reaction between GG and vinyl acetate and PHGG through esterification reaction with phthalic anhydride. The modified GG was characterized by solubility test, Fourier-transform infra-red (FTIR) spectroscopy, proton nuclear magnetic resonance (H-1 NMR) spectroscopy, X-ray diffractometry (XRD) and thermogravimetric analysis. Swelling properties of GGA and PHGG hydrogels in water were evaluated. Findings These two types of modified GG have better solubility such as in dimethyl sulfoxide and N,N-dimethylformamide but no true organosolubility was achieved. The modifications were confirmed through FTIR with new absorption peaks at 1,733 cm(-1) for GGA and 1,709 cm(-1) for PHGG coupled with observed substitution peaks at 1.80 to 2.20 ppm and 7.40 to 7.90 ppm, respectively, from H-1 NMR spectroscopies. XRD revealed both GGA and PHGG are less crystalline than native GG. GGA was found to be more thermally stable than native GG, whereas PHGG was slightly less thermally stable than native GG. The swelling property in distilled water for native GG, PHGG and GGA was 918.43 +/- 46.62%, 537.04 +/- 2.87% and 393.04 +/- 13.42%, respectively. Research limitations/implications The GGA and PHGG hydrogels are expected to be useful for biomedical fields such as tissue engineering and drug-delivery. Originality/value Modifications of native GG into GGA using vinyl acetate and PHGG using phthalic anhydride are novel.
format	Article
author	Mazlan, Mazrina Rizwan, Muhammad Azzahari, Ahmad Danial Selvanathan, Vidhya Sonsudin, Faridah Shahabudin, Nurshafiza
author_facet	Mazlan, Mazrina Rizwan, Muhammad Azzahari, Ahmad Danial Selvanathan, Vidhya Sonsudin, Faridah Shahabudin, Nurshafiza
author_sort	Mazlan, Mazrina
title	The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
title_short	The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
title_full	The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
title_fullStr	The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
title_full_unstemmed	The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
title_sort	impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels
publisher	Emerald
publishDate	2021
url	http://eprints.um.edu.my/28541/
_version_	1744649124872978432
score	13.211869

The impact of substitution of two hydrophobic moieties on the properties of guar gum based hydrogels

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