Staff View: Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions

Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions

There is much interest in the use of deoxyribonucleic acid (DNA) for applications in the field of molecular electronics and biosensors because of its unique self-assembling behaviour. Studying its sequence-specific electronic properties is one such analysis that could be employed as a tool for under...

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Main Authors:	Rizan, Nastaran, Tajuddin, Hairul Anuar, Tan, Yee Shin, Abdullah, Zanariah, Idris, Azila, Periasamy, Vengadesh
Format:	Article
Published:	Springer 2021
Subjects:	TA Engineering (General). Civil engineering (General)
Online Access:	http://eprints.um.edu.my/28341/
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spelling	my.um.eprints.283412022-04-07T03:19:59Z http://eprints.um.edu.my/28341/ Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions Rizan, Nastaran Tajuddin, Hairul Anuar Tan, Yee Shin Abdullah, Zanariah Idris, Azila Periasamy, Vengadesh TA Engineering (General). Civil engineering (General) There is much interest in the use of deoxyribonucleic acid (DNA) for applications in the field of molecular electronics and biosensors because of its unique self-assembling behaviour. Studying its sequence-specific electronic properties is one such analysis that could be employed as a tool for understanding mechanisms of charge transfer for integration into DNA-based devices. Although known to be reasonably stable in aqueous solution, environmental factors can affect the helical structure, resulting in significantly attenuated electronic profile. DNA molecules are also not stable when stored for long periods in solution form at room temperature prompting many interests for solvents in which DNA structures exhibit long-term stability. Ionic liquid (IL), 1-butyl-3-methylimidazolium acetate (BMIM]Ace]), is a potential solvent that ensures long-term stability of DNA. Therefore, in this work, the effect of IL on basidiomycetes DNAs integrated within an aluminium (Al)-indium tin oxide (ITO) Schottky junction was investigated. Significant improvement in the rectifying profiles was observed for DNA dissolved in BMIM]Ace] (IL/DNA) compared to DNA in aqueous solution (aq/DNA) without the addition of IL when stored at different temperatures and time intervals. In general, the junction structure exhibited insulating behaviour when DNA was stored at room temperature for three months. This results in loss of its structure and stability for long periods of use at room temperature. Meanwhile, IL sample itself (control) shows a linear conductive profile. Furthermore, different solid-state parameters calculated allow us to understand the charge transfer mechanism in DNA molecules as a function of IL. Springer 2021-01-26 Article PeerReviewed Rizan, Nastaran and Tajuddin, Hairul Anuar and Tan, Yee Shin and Abdullah, Zanariah and Idris, Azila and Periasamy, Vengadesh (2021) Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions. Applied Physics A, 127 (2). ISSN 0947-8396, DOI https://doi.org/10.1007/s00339-021-04303-4 <https://doi.org/10.1007/s00339-021-04303-4>. 10.1007/s00339-021-04303-4
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	TA Engineering (General). Civil engineering (General)
spellingShingle	TA Engineering (General). Civil engineering (General) Rizan, Nastaran Tajuddin, Hairul Anuar Tan, Yee Shin Abdullah, Zanariah Idris, Azila Periasamy, Vengadesh Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
description	There is much interest in the use of deoxyribonucleic acid (DNA) for applications in the field of molecular electronics and biosensors because of its unique self-assembling behaviour. Studying its sequence-specific electronic properties is one such analysis that could be employed as a tool for understanding mechanisms of charge transfer for integration into DNA-based devices. Although known to be reasonably stable in aqueous solution, environmental factors can affect the helical structure, resulting in significantly attenuated electronic profile. DNA molecules are also not stable when stored for long periods in solution form at room temperature prompting many interests for solvents in which DNA structures exhibit long-term stability. Ionic liquid (IL), 1-butyl-3-methylimidazolium acetate (BMIM]Ace]), is a potential solvent that ensures long-term stability of DNA. Therefore, in this work, the effect of IL on basidiomycetes DNAs integrated within an aluminium (Al)-indium tin oxide (ITO) Schottky junction was investigated. Significant improvement in the rectifying profiles was observed for DNA dissolved in BMIM]Ace] (IL/DNA) compared to DNA in aqueous solution (aq/DNA) without the addition of IL when stored at different temperatures and time intervals. In general, the junction structure exhibited insulating behaviour when DNA was stored at room temperature for three months. This results in loss of its structure and stability for long periods of use at room temperature. Meanwhile, IL sample itself (control) shows a linear conductive profile. Furthermore, different solid-state parameters calculated allow us to understand the charge transfer mechanism in DNA molecules as a function of IL.
format	Article
author	Rizan, Nastaran Tajuddin, Hairul Anuar Tan, Yee Shin Abdullah, Zanariah Idris, Azila Periasamy, Vengadesh
author_facet	Rizan, Nastaran Tajuddin, Hairul Anuar Tan, Yee Shin Abdullah, Zanariah Idris, Azila Periasamy, Vengadesh
author_sort	Rizan, Nastaran
title	Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
title_short	Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
title_full	Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
title_fullStr	Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
title_full_unstemmed	Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions
title_sort	effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes dnas integrated within schottky-like junctions
publisher	Springer
publishDate	2021
url	http://eprints.um.edu.my/28341/
_version_	1735409555257425920
score	13.211869

Effect of ionic liquid on the long-term structural and chemical stability of basidiomycetes DNAs integrated within Schottky-like junctions

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