Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review

Crocus sativus L., a medicinally important species of the Iridaceae family which produces the herb saffron, plays an effective role in combating various pathogenic disorders including cancers and cardiovascular diseases. Apart from its conventional colorant and aroma-inducing attributes, various phy...

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Main Authors: Khan, A., Muhamad, Nur Airina, Taha, R. M., Mohamad, J., Al-Shara, B.
Format: Article
Published: Universiti Putra Malaysia 2021
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Online Access:http://eprints.um.edu.my/28123/
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spelling my.um.eprints.281232022-07-25T08:29:31Z http://eprints.um.edu.my/28123/ Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review Khan, A. Muhamad, Nur Airina Taha, R. M. Mohamad, J. Al-Shara, B. Q Science (General) Crocus sativus L., a medicinally important species of the Iridaceae family which produces the herb saffron, plays an effective role in combating various pathogenic disorders including cancers and cardiovascular diseases. Apart from its conventional colorant and aroma-inducing attributes, various phytochemical compounds associated with saffron are now being intensively studied. More than 300 phytochemical compounds, derived from saffron stigmas alone, belong to various classes of secondary metabolites such as carotenoids, terpenoids, flavonoids, and anthocyanins; and they have immense therapeutic applications. Furthermore, pharmacogenomic studies of saffron extracts have revealed promising biocompatible and anticancer potentials against various drug-resistant cell lines which reduce cellular division and proliferation of malignant cells. Keeping in view with the numerous pharmacological properties associated with saffron, the present review explicitly discusses the role of its elemental contents in the prevention and treatment of various cancers and cardiovascular ailments. (C) All Rights Reserved Universiti Putra Malaysia 2021-10 Article PeerReviewed Khan, A. and Muhamad, Nur Airina and Taha, R. M. and Mohamad, J. and Al-Shara, B. (2021) Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review. International Food Research Journal, 28 (5). pp. 871-892. ISSN 1985-4668,
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
spellingShingle Q Science (General)
Khan, A.
Muhamad, Nur Airina
Taha, R. M.
Mohamad, J.
Al-Shara, B.
Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
description Crocus sativus L., a medicinally important species of the Iridaceae family which produces the herb saffron, plays an effective role in combating various pathogenic disorders including cancers and cardiovascular diseases. Apart from its conventional colorant and aroma-inducing attributes, various phytochemical compounds associated with saffron are now being intensively studied. More than 300 phytochemical compounds, derived from saffron stigmas alone, belong to various classes of secondary metabolites such as carotenoids, terpenoids, flavonoids, and anthocyanins; and they have immense therapeutic applications. Furthermore, pharmacogenomic studies of saffron extracts have revealed promising biocompatible and anticancer potentials against various drug-resistant cell lines which reduce cellular division and proliferation of malignant cells. Keeping in view with the numerous pharmacological properties associated with saffron, the present review explicitly discusses the role of its elemental contents in the prevention and treatment of various cancers and cardiovascular ailments. (C) All Rights Reserved
format Article
author Khan, A.
Muhamad, Nur Airina
Taha, R. M.
Mohamad, J.
Al-Shara, B.
author_facet Khan, A.
Muhamad, Nur Airina
Taha, R. M.
Mohamad, J.
Al-Shara, B.
author_sort Khan, A.
title Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
title_short Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
title_full Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
title_fullStr Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
title_full_unstemmed Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review
title_sort therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: a review
publisher Universiti Putra Malaysia
publishDate 2021
url http://eprints.um.edu.my/28123/
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score 13.211869