The potential use of volatile biomarkers for malaria diagnosis

Pathogens may change the odor and odor-related biting behavior of the vector and host to enhance pathogen transmission. In recent years, volatile biomarker investigations have emerged to identify odors that are differentially and specifically released by pathogens and plants, or the pathogen-infecte...

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Main Authors: Chai, Hwa Chia, Chua, Kek Heng
Format: Article
Published: MDPI 2021
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Online Access:http://eprints.um.edu.my/26868/
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spelling my.um.eprints.268682022-04-21T06:41:43Z http://eprints.um.edu.my/26868/ The potential use of volatile biomarkers for malaria diagnosis Chai, Hwa Chia Chua, Kek Heng R Medicine (General) Pathogens may change the odor and odor-related biting behavior of the vector and host to enhance pathogen transmission. In recent years, volatile biomarker investigations have emerged to identify odors that are differentially and specifically released by pathogens and plants, or the pathogen-infected or even cancer patients. Several studies have reported odors or volatile biomarkers specifically detected from the breath and skin of malaria-infected individuals. This review will discuss the potential use of these odors or volatile biomarkers for the diagnosis of malaria. This approach not only allows for the non-invasive mean of sample collection but also opens up the opportunity to develop a biosensor for malaria diagnosis in low-resource settings. MDPI 2021-12 Article PeerReviewed Chai, Hwa Chia and Chua, Kek Heng (2021) The potential use of volatile biomarkers for malaria diagnosis. Diagnostics, 11 (12). ISSN 2075-4418, DOI https://doi.org/10.3390/diagnostics11122244 <https://doi.org/10.3390/diagnostics11122244>. 10.3390/diagnostics11122244
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Chai, Hwa Chia
Chua, Kek Heng
The potential use of volatile biomarkers for malaria diagnosis
description Pathogens may change the odor and odor-related biting behavior of the vector and host to enhance pathogen transmission. In recent years, volatile biomarker investigations have emerged to identify odors that are differentially and specifically released by pathogens and plants, or the pathogen-infected or even cancer patients. Several studies have reported odors or volatile biomarkers specifically detected from the breath and skin of malaria-infected individuals. This review will discuss the potential use of these odors or volatile biomarkers for the diagnosis of malaria. This approach not only allows for the non-invasive mean of sample collection but also opens up the opportunity to develop a biosensor for malaria diagnosis in low-resource settings.
format Article
author Chai, Hwa Chia
Chua, Kek Heng
author_facet Chai, Hwa Chia
Chua, Kek Heng
author_sort Chai, Hwa Chia
title The potential use of volatile biomarkers for malaria diagnosis
title_short The potential use of volatile biomarkers for malaria diagnosis
title_full The potential use of volatile biomarkers for malaria diagnosis
title_fullStr The potential use of volatile biomarkers for malaria diagnosis
title_full_unstemmed The potential use of volatile biomarkers for malaria diagnosis
title_sort potential use of volatile biomarkers for malaria diagnosis
publisher MDPI
publishDate 2021
url http://eprints.um.edu.my/26868/
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score 13.211869