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Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature

The advancement in science and research has led to development of medical maggots which feed exclusively on dead tissue. Medical maggots have three important functions namely debridement, disinfection, and stimulation of wound healing. The modern use of medical maggots now goes by the term ``Maggot...

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Main Authors: Phang, Zi Hao, Khoo, Saw Sian, Gunasagaran, Jayaletchumi, Ahmad, Tunku Sara Tunku
Format: Article
Published: SAGE Publications (UK and US) 2021
Subjects:
R Medicine (General)
Online Access:http://eprints.um.edu.my/26367/
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spelling my.um.eprints.263672022-02-24T01:59:52Z http://eprints.um.edu.my/26367/ Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature Phang, Zi Hao Khoo, Saw Sian Gunasagaran, Jayaletchumi Ahmad, Tunku Sara Tunku R Medicine (General) The advancement in science and research has led to development of medical maggots which feed exclusively on dead tissue. Medical maggots have three important functions namely debridement, disinfection, and stimulation of wound healing. The modern use of medical maggots now goes by the term ``Maggot Debridement Therapy'' (MDT) for use in wound management. MDT is still used infrequently due to the effectiveness of surgical debridement and antibiotics for treatment of wound infection. Lately, there was emergence of Multi-Drug Resistant Organism (MDRO) likely due to inappropriate antibiotics usage. Maggot secretions have been shown to be effective in inhibiting some MDRO, for example, Methicillin-resistant Staphylococcus aureus, thus making MDT an attractive option for wounds with MDRO. We report two patients with multiple medical comorbidities, diagnosed with serious MDRO Diabetic Hand Infections treated with three cycles of MDT followed by Negative Pressure Wound Therapy. SAGE Publications (UK and US) 2021-09 Article PeerReviewed Phang, Zi Hao and Khoo, Saw Sian and Gunasagaran, Jayaletchumi and Ahmad, Tunku Sara Tunku (2021) Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature. Journal of Orthopaedic Surgery, 29 (3). ISSN 2309-4990, DOI https://doi.org/10.1177/23094990211067302 <https://doi.org/10.1177/23094990211067302>. 10.1177/23094990211067302
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Phang, Zi Hao
Khoo, Saw Sian
Gunasagaran, Jayaletchumi
Ahmad, Tunku Sara Tunku
Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
description The advancement in science and research has led to development of medical maggots which feed exclusively on dead tissue. Medical maggots have three important functions namely debridement, disinfection, and stimulation of wound healing. The modern use of medical maggots now goes by the term ``Maggot Debridement Therapy'' (MDT) for use in wound management. MDT is still used infrequently due to the effectiveness of surgical debridement and antibiotics for treatment of wound infection. Lately, there was emergence of Multi-Drug Resistant Organism (MDRO) likely due to inappropriate antibiotics usage. Maggot secretions have been shown to be effective in inhibiting some MDRO, for example, Methicillin-resistant Staphylococcus aureus, thus making MDT an attractive option for wounds with MDRO. We report two patients with multiple medical comorbidities, diagnosed with serious MDRO Diabetic Hand Infections treated with three cycles of MDT followed by Negative Pressure Wound Therapy.
format Article
author Phang, Zi Hao
Khoo, Saw Sian
Gunasagaran, Jayaletchumi
Ahmad, Tunku Sara Tunku
author_facet Phang, Zi Hao
Khoo, Saw Sian
Gunasagaran, Jayaletchumi
Ahmad, Tunku Sara Tunku
author_sort Phang, Zi Hao
title Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
title_short Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
title_full Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
title_fullStr Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
title_full_unstemmed Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature
title_sort clinical outcome of maggot debridement therapy followed by negative pressure wound therapy for chronic hand wound with multi-drug resistant organism infection: two cases and review of the literature
publisher SAGE Publications (UK and US)
publishDate 2021
url http://eprints.um.edu.my/26367/
_version_ 1735409403407892480
score 13.211869

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