Direct priming of CD8 + T cells persists in the face of Cowpox Virus Inhibitors of antigen presentation

Vaccinia virus (VACV) was the vaccine used to eradicate smallpox and is being repurposed as a vaccine vector. CD8(+) T cells are key antiviral mediators but require priming to become effector or memory cells. Priming requires an interaction with dendritic cells that are either infected (direct primi...

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Bibliographic Details
Main Authors: Lin, Leon C. W., Croft, Sarah N., Croft, Nathan P., Wong, Yik Chun, Smith, Stewart A., Tang, Swee-Seong, Purcell, Anthony W., Tscharke, David C., Shisler, Joanna L.
Format: Article
Published: 2021
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Online Access:http://eprints.um.edu.my/26298/
https://doi.org/10.1128/JVI.00186-21
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