Direct priming of CD8 + T cells persists in the face of Cowpox Virus Inhibitors of antigen presentation
Vaccinia virus (VACV) was the vaccine used to eradicate smallpox and is being repurposed as a vaccine vector. CD8(+) T cells are key antiviral mediators but require priming to become effector or memory cells. Priming requires an interaction with dendritic cells that are either infected (direct primi...
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Main Authors: | , , , , , , , , |
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Format: | Article |
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2021
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Online Access: | http://eprints.um.edu.my/26298/ https://doi.org/10.1128/JVI.00186-21 |
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