Clinical drug-resistant nodular sclerosing Hodgkin's lymphoma is associated with decreased bcl-2 expression in the surrounding lymphocytes and with increased bcl-2 expression in the Reed-Sternberg cells
Identification of patients with Hodgkin's lymphoma who are primary refractory to chemotherapy will have great impact on treatment planning. Several studies have indicated that up-regulation of the bcl-2 proto-oncogene expression in non-Hodgkin's lymphoma can cause resistance to chemotherap...
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Main Authors: | Van Spronsen, D.J., Peh, Suat Cheng, Vrints, L W, Van Imhoff, G W, Poppema, S |
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Format: | Article |
Published: |
Wiley
2003
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Subjects: | |
Online Access: | http://eprints.um.edu.my/26006/ https://doi.org/10.1046/j.1365-2559.2000.01010.x |
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