In-silico Studies of the Antiproliferative Activity of New Anilinoquinazoline Derivatives Against NSCLC Cells

The current reversible epidermal growth factor (EGFR) tyrosine kinase inhibitors of non-small cell lung cancer (NSCLC) have been resisted by T790M mutation, while the irreversible inhibitors introduced to overcome the mutation have faced resistance from C979S mutation. In the effort to discover pote...

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Bibliographic Details
Main Authors: Abdulwahab, Muhammad Kumayl, Tan, Ke Han, Dzulkeflee, Rashidi, Leong, Kok Hoong, Heh, Choon Han, Ariffin, Azhar
Format: Article
Published: Elsevier 2021
Subjects:
Online Access:http://eprints.um.edu.my/25985/
https://doi.org/10.1016/j.molstruc.2020.129786
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