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Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia

A retrospective study of odontogenic keratocysts in the Malaysia-Singapore region was done. The purpose of this study is to present the clinicopathological features of odontogenic keratocysts in the Oriental population and to compare the data with those from other reported studies. Biopsy records fr...

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Main Authors: Ngeow, Wei Cheong, Zain, R.B., Yeo, J.F., Chai, W.L.
Format: Article
Language:English
Published: AMER ASSOC DENTAL RESEARCH 1999
Subjects:
Oral surger
Online Access:http://eprints.um.edu.my/2567/1/Clinicopathologic_study_of_odontogenic_keratocysts_in_Singapore_and_Malaysia.pdf
http://eprints.um.edu.my/2567/
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spelling my.um.eprints.25672019-09-27T08:39:20Z http://eprints.um.edu.my/2567/ Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia Ngeow, Wei Cheong Zain, R.B. Yeo, J.F. Chai, W.L. Oral surger A retrospective study of odontogenic keratocysts in the Malaysia-Singapore region was done. The purpose of this study is to present the clinicopathological features of odontogenic keratocysts in the Oriental population and to compare the data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts in Malaysia and Singapore showed that there were 42.6% female and 57.4% male patients. The cysts occurred in 75.4% Chinese, 6.6% Malays, 9.8% Indian, and 8.2% other ethnic groups. The mean age of these patients was 26.98 ± 15.38 years with peak incidence in the second to fourth decades. The location of the lesion was more often in the mandible (65.5%) than the maxilla (31.0%). There is marked predilection for the posterior mandible. Odontogenic keratocysts presenting at the site of dentigerous a cyst was observed in 7 cases (11.5%). Histologically, 90.2% of the cyst were lined by parakeratinised stratified squamous epithelium while only 3.3% of the cyst with orthokeratinised stratified squamous epithelium. Mixed parakeratinised and orthokeratinised epithelial lining was observed in 4 cases (6.5%). Inflammation of cyst wall was found in 42 cases (68.8%). Stellate-like inflamed lining epithelium was observed in 9.8% of the cases while 6.6% of the cases demonstrated Rushton bodies in the epithelial lining. Keratin in the lumen was observed in 19.7% of the cases. Satellite cyst was observed in only 6 cases (9.8%). In conclusion, most clinical and histological features seen in this study similar to that for the Caucasian. The only clinical feature that differs is the peak incidence which ranged from the second to fourth decades with an absence of the second peak for our study AMER ASSOC DENTAL RESEARCH 1999 Article PeerReviewed application/pdf en http://eprints.um.edu.my/2567/1/Clinicopathologic_study_of_odontogenic_keratocysts_in_Singapore_and_Malaysia.pdf Ngeow, Wei Cheong and Zain, R.B. and Yeo, J.F. and Chai, W.L. (1999) Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia. Journal of Dental Research, 78 (5). p. 1180. ISSN 0022-0345
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic Oral surger
spellingShingle Oral surger
Ngeow, Wei Cheong
Zain, R.B.
Yeo, J.F.
Chai, W.L.
Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
description A retrospective study of odontogenic keratocysts in the Malaysia-Singapore region was done. The purpose of this study is to present the clinicopathological features of odontogenic keratocysts in the Oriental population and to compare the data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts in Malaysia and Singapore showed that there were 42.6% female and 57.4% male patients. The cysts occurred in 75.4% Chinese, 6.6% Malays, 9.8% Indian, and 8.2% other ethnic groups. The mean age of these patients was 26.98 ± 15.38 years with peak incidence in the second to fourth decades. The location of the lesion was more often in the mandible (65.5%) than the maxilla (31.0%). There is marked predilection for the posterior mandible. Odontogenic keratocysts presenting at the site of dentigerous a cyst was observed in 7 cases (11.5%). Histologically, 90.2% of the cyst were lined by parakeratinised stratified squamous epithelium while only 3.3% of the cyst with orthokeratinised stratified squamous epithelium. Mixed parakeratinised and orthokeratinised epithelial lining was observed in 4 cases (6.5%). Inflammation of cyst wall was found in 42 cases (68.8%). Stellate-like inflamed lining epithelium was observed in 9.8% of the cases while 6.6% of the cases demonstrated Rushton bodies in the epithelial lining. Keratin in the lumen was observed in 19.7% of the cases. Satellite cyst was observed in only 6 cases (9.8%). In conclusion, most clinical and histological features seen in this study similar to that for the Caucasian. The only clinical feature that differs is the peak incidence which ranged from the second to fourth decades with an absence of the second peak for our study
format Article
author Ngeow, Wei Cheong
Zain, R.B.
Yeo, J.F.
Chai, W.L.
author_facet Ngeow, Wei Cheong
Zain, R.B.
Yeo, J.F.
Chai, W.L.
author_sort Ngeow, Wei Cheong
title Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
title_short Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
title_full Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
title_fullStr Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
title_full_unstemmed Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia
title_sort clinicopathologic study of odontogenic keratocysts in singapore and malaysia
publisher AMER ASSOC DENTAL RESEARCH
publishDate 1999
url http://eprints.um.edu.my/2567/1/Clinicopathologic_study_of_odontogenic_keratocysts_in_Singapore_and_Malaysia.pdf
http://eprints.um.edu.my/2567/
_version_ 1646210100082245632
score 13.211869

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