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Outcome of expandable endoprosthesis: A single centre retrospective review

Purpose: Expandable endoprosthesis allows limb salvage in children with an option to leading a better life. However, the revision rate and implant-related complications impose as a limitation in the skeletal immature. This study investigates the functional outcomes and complications related to expan...

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Main Authors: Singh, Vivek Ajit, Kunasingh, Dinesh Earnest, Haseeb, Amber, Yasin, Nor Faissal
Format: Article
Published: SAGE Publications (UK and US) 2019
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/24372/
https://doi.org/10.1177/2309499019850313
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spelling my.um.eprints.243722020-05-27T02:16:32Z http://eprints.um.edu.my/24372/ Outcome of expandable endoprosthesis: A single centre retrospective review Singh, Vivek Ajit Kunasingh, Dinesh Earnest Haseeb, Amber Yasin, Nor Faissal R Medicine Purpose: Expandable endoprosthesis allows limb salvage in children with an option to leading a better life. However, the revision rate and implant-related complications impose as a limitation in the skeletal immature. This study investigates the functional outcomes and complications related to expandable endoprosthesis in our centre. Materials and Methods: Twenty surviving patients with expandable endoprosthesis from 2006 till 2015 were scored using Musculoskeletal Tumour Society (MSTS) outcomes instrument and reviewed retrospectively for range of motion of respected joints, limb length discrepancy, number of surgeries performed, complications and oncological outcomes. Patients with less than 2 years of follow-up were excluded from this study. Results: Forty-five percentage patients reached skeletal maturity with initial growing endoprosthesis and 25% of patients were revised to adult modular prosthesis. One hundred fifty-seven surgeries were performed over the 9-year period. The average MSTS score was 90.83%. The mortality rate was 10% within 5 years due to advanced disease. Infection and implant failure rate was 15% each. The event-free survival was 50% and overall survival rate was 90%. Conclusion: There is no single best option for reconstruction in skeletally immature. This study demonstrates a favourable functional and survival outcome of paediatric patients with expandable endoprosthesis. The excellent MSTS functional scores reflect that patients were satisfied and adjusted well to activities of daily living following surgery despite the complications. © The Author(s) 2019. SAGE Publications (UK and US) 2019 Article PeerReviewed Singh, Vivek Ajit and Kunasingh, Dinesh Earnest and Haseeb, Amber and Yasin, Nor Faissal (2019) Outcome of expandable endoprosthesis: A single centre retrospective review. Journal of Orthopaedic Surgery, 27 (2). p. 230949901985031. ISSN 2309-4990 https://doi.org/10.1177/2309499019850313 doi:10.1177/2309499019850313
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Singh, Vivek Ajit
Kunasingh, Dinesh Earnest
Haseeb, Amber
Yasin, Nor Faissal
Outcome of expandable endoprosthesis: A single centre retrospective review
description Purpose: Expandable endoprosthesis allows limb salvage in children with an option to leading a better life. However, the revision rate and implant-related complications impose as a limitation in the skeletal immature. This study investigates the functional outcomes and complications related to expandable endoprosthesis in our centre. Materials and Methods: Twenty surviving patients with expandable endoprosthesis from 2006 till 2015 were scored using Musculoskeletal Tumour Society (MSTS) outcomes instrument and reviewed retrospectively for range of motion of respected joints, limb length discrepancy, number of surgeries performed, complications and oncological outcomes. Patients with less than 2 years of follow-up were excluded from this study. Results: Forty-five percentage patients reached skeletal maturity with initial growing endoprosthesis and 25% of patients were revised to adult modular prosthesis. One hundred fifty-seven surgeries were performed over the 9-year period. The average MSTS score was 90.83%. The mortality rate was 10% within 5 years due to advanced disease. Infection and implant failure rate was 15% each. The event-free survival was 50% and overall survival rate was 90%. Conclusion: There is no single best option for reconstruction in skeletally immature. This study demonstrates a favourable functional and survival outcome of paediatric patients with expandable endoprosthesis. The excellent MSTS functional scores reflect that patients were satisfied and adjusted well to activities of daily living following surgery despite the complications. © The Author(s) 2019.
format Article
author Singh, Vivek Ajit
Kunasingh, Dinesh Earnest
Haseeb, Amber
Yasin, Nor Faissal
author_facet Singh, Vivek Ajit
Kunasingh, Dinesh Earnest
Haseeb, Amber
Yasin, Nor Faissal
author_sort Singh, Vivek Ajit
title Outcome of expandable endoprosthesis: A single centre retrospective review
title_short Outcome of expandable endoprosthesis: A single centre retrospective review
title_full Outcome of expandable endoprosthesis: A single centre retrospective review
title_fullStr Outcome of expandable endoprosthesis: A single centre retrospective review
title_full_unstemmed Outcome of expandable endoprosthesis: A single centre retrospective review
title_sort outcome of expandable endoprosthesis: a single centre retrospective review
publisher SAGE Publications (UK and US)
publishDate 2019
url http://eprints.um.edu.my/24372/
https://doi.org/10.1177/2309499019850313
_version_ 1669007996611461120
score 13.211869

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