Cover Image

Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application

Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and po...

Full description

Saved in:
Bibliographic Details
Main Authors: Misni, Norashiqin, Nor, Zurainee Mohamed, Ahmad, Rohani
Format: Article
Published: School of Pharmacy, Shahid Beheshti University of Medical Sciences 2019
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/24025/
http://ijpr.sbmu.ac.ir/article_2351.html
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.um.eprints.24025
record_format eprints
spelling my.um.eprints.240252020-03-12T03:33:05Z http://eprints.um.edu.my/24025/ Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application Misni, Norashiqin Nor, Zurainee Mohamed Ahmad, Rohani R Medicine Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using the interfacial precipitation chemistry technique. The microencapsulated CGPO was then formulated into lotion form to produce topical repellent formulation. This study includes the characterization of microcapsules with regards to the morphology, size distribution, zeta potential, Fourier Transmission Infrared spectrophotometer (FTIR), and Thermogravity analysis (TGA). The effectiveness of the microencapsulated CGPO-lotion formulation against mosquitoes was evaluated in the laboratory setting. Results indicated that CGPO have been successfully encapsulated with 6.5 µm in diameter and zeta potential values,-47.9 mV. The FTIR analysis spectrum indicated the presence of interaction between the wall materials in microcapsules. The TGA analysis demonstrated that microencapsulation improved the thermal stability of CGPO. Repellency assay revealed that microencapsulated CGPO-based formulation possessed excellent effect compared with pure CGPO. In conclusion, CGPO was successfully encapsulated and the microencapsulation aid to improve the repellency effect of CGPO against mosquito bites. © 2019, Iranian Journal of Pharmaceutical Research. All rights reserved. School of Pharmacy, Shahid Beheshti University of Medical Sciences 2019 Article PeerReviewed Misni, Norashiqin and Nor, Zurainee Mohamed and Ahmad, Rohani (2019) Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application. Iranian Journal of Pharmaceutical Research, 18 (1). pp. 198-209. ISSN 1735-0328 http://ijpr.sbmu.ac.ir/article_2351.html doi:10.22037/ijpr.2019.2351
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Misni, Norashiqin
Nor, Zurainee Mohamed
Ahmad, Rohani
Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
description Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using the interfacial precipitation chemistry technique. The microencapsulated CGPO was then formulated into lotion form to produce topical repellent formulation. This study includes the characterization of microcapsules with regards to the morphology, size distribution, zeta potential, Fourier Transmission Infrared spectrophotometer (FTIR), and Thermogravity analysis (TGA). The effectiveness of the microencapsulated CGPO-lotion formulation against mosquitoes was evaluated in the laboratory setting. Results indicated that CGPO have been successfully encapsulated with 6.5 µm in diameter and zeta potential values,-47.9 mV. The FTIR analysis spectrum indicated the presence of interaction between the wall materials in microcapsules. The TGA analysis demonstrated that microencapsulation improved the thermal stability of CGPO. Repellency assay revealed that microencapsulated CGPO-based formulation possessed excellent effect compared with pure CGPO. In conclusion, CGPO was successfully encapsulated and the microencapsulation aid to improve the repellency effect of CGPO against mosquito bites. © 2019, Iranian Journal of Pharmaceutical Research. All rights reserved.
format Article
author Misni, Norashiqin
Nor, Zurainee Mohamed
Ahmad, Rohani
author_facet Misni, Norashiqin
Nor, Zurainee Mohamed
Ahmad, Rohani
author_sort Misni, Norashiqin
title Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_short Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_full Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_fullStr Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_full_unstemmed Microencapsulation of Citrus Grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_sort microencapsulation of citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
publisher School of Pharmacy, Shahid Beheshti University of Medical Sciences
publishDate 2019
url http://eprints.um.edu.my/24025/
http://ijpr.sbmu.ac.ir/article_2351.html
_version_ 1662755212546277376
score 13.211869

Similar Items