Synthesis of γ-N-modified 8-oxo-2’-deoxyguanosine triphosphate and its characterization

8-OxodGTP is generated by the reaction between dGTP and reactive oxygen species and a considered mutagenic nucleotide. It can be incorporated into the duplex DNA during replication processes by the DNA polymerase, and thus the repair enzyme removes oxodGTP from the nucleotide pools in living cells....

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Bibliographic Details
Main Authors: Thavoncharoensub, Ninticha, Maruyama, Kento, Heh, Choon Han, Leong, Kok Hoong, Shi, Hui, Shigematsu, Yoshiharu, Sasaki, Shigeki, Taniguchi, Yosuke
Format: Article
Published: Taylor & Francis 2019
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Online Access:http://eprints.um.edu.my/23245/
https://doi.org/10.1080/15257770.2019.1586919
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