Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to agerelated vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. Th...
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Main Authors: | , , , , , |
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Format: | Article |
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Leibniz Research Centre for Working Environment and Human Factors
2019
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Subjects: | |
Online Access: | http://eprints.um.edu.my/23160/ https://www.excli.de/vol18/Wong_03092019_proof.pdf |
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