Synergistic Growth Inhibition by Afatinib and Trametinib in Preclinical Oral Squamous Cell Carcinoma Models
Background: Given that aberrant activation of epidermal growth factor receptor family receptors (ErbB) is a common event in oral squamous cell carcinoma, and that high expression of these receptor proteins is often associated with poor prognosis, this rationalizes the approach of targeting ErbB sign...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Published: |
Springer
2019
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/23103/ https://doi.org/10.1007/s11523-019-00626-8 |
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