Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report
Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were...
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| Main Authors: | , , , , |
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| Format: | Article |
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Springer Verlag
2017
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/22842/ https://doi.org/10.1007/s12055-017-0545-7 |
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| Summary: | Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were positive, aided by computerized tomography-guided histological confirmation. Despite medical therapy, there was inadequate resolution, and surgical resection was performed. On follow-up, investigations showed complete resolution, and the patient has remained disease-free at 5 years. This highlights the importance of looking for other sites in resistant cryptococcal meningitis and the value of cardiothoracic intervention for slowly resolving pulmonary cryptococcomas. |
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