Restoring the IL-1β/NF-κB-induced impaired chondrogenesis by diallyl disulfide in human adipose-derived mesenchymal stem cells via attenuation of reactive oxygen species and elevation of antioxidant enzymes
Strategies based on mesenchymal stem cell (MSC) therapy for restoring injured articular cartilage are not effective enough in osteoarthritis (OA). Due to the enhanced inflammation and oxidative stress in OA microenvironment, differentiation of MSCs into chondrocytes would be impaired. This study aim...
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Main Authors: | , , , , |
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Format: | Article |
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Springer
2018
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Online Access: | http://eprints.um.edu.my/22368/ https://doi.org/10.1007/s00441-018-2825-y |
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