Genetic diversity of rodent blastocystis sp. From peninsular Malaysia

Rodents are ubiquitous zoonotic vectors for many human pathogens including Blastocystis sp. In this study, we examined the prevalence and subtypes of Blastocystis sp. in rodents captured from Peninsular Malaysia. A total of 293 rodents predominantly brown rat (Rattus norvegicus) (290 of 293, 99.0%)...

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Main Authors: Farah Haziqah, Meor Termizi, Mohd Zain, Siti Nursheena, Chandrawathani, Panchacharam, Premaalatha, B., Mohd Khalid, Mohd Khairul Nizam, Arutchelvan, R., Govind, Suresh Kumar
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Published: Malaysian Society of Parasitology and Tropical Medicine 2018
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Online Access:http://eprints.um.edu.my/22092/
http://msptm.org/files/Vol35No2/586-592-Suresh-K.pdf
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spelling my.um.eprints.220922019-08-27T02:45:42Z http://eprints.um.edu.my/22092/ Genetic diversity of rodent blastocystis sp. From peninsular Malaysia Farah Haziqah, Meor Termizi Mohd Zain, Siti Nursheena Chandrawathani, Panchacharam Premaalatha, B. Mohd Khalid, Mohd Khairul Nizam Arutchelvan, R. Govind, Suresh Kumar Q Science (General) QH Natural history R Medicine Rodents are ubiquitous zoonotic vectors for many human pathogens including Blastocystis sp. In this study, we examined the prevalence and subtypes of Blastocystis sp. in rodents captured from Peninsular Malaysia. A total of 293 rodents predominantly brown rat (Rattus norvegicus) (290 of 293, 99.0%) and house shrew (Suncus murinus) (3 of 293, 1.0 %), were captured in the vicinity of popular eateries in two cities (Kuala Lumpur and Ipoh) in Peninsular Malaysia. In vitro cultivation method showed presence of Blastocystis sp. in approximately half (133 of 290, 45.9%) of the brown rats tested. Among the 47 Blastocystis isolates subtyped using partial small subunit ribosomal RNA gene analysis, ST4 was the most abundant (43 of 47, 91.5%) followed by ST1 (2 of 47, 4.3%), ST5 (1 of 47, 2.1%) and ST7 (1 of 47, 2.1%). Our findings highlighted the importance of rodents as a source of Blastocystis sp. infection in Malaysia and showed the high prevalence of ST4 within the rodent population infected with Blastocystis sp. Malaysian Society of Parasitology and Tropical Medicine 2018 Article PeerReviewed Farah Haziqah, Meor Termizi and Mohd Zain, Siti Nursheena and Chandrawathani, Panchacharam and Premaalatha, B. and Mohd Khalid, Mohd Khairul Nizam and Arutchelvan, R. and Govind, Suresh Kumar (2018) Genetic diversity of rodent blastocystis sp. From peninsular Malaysia. Tropical Biomedicine, 35 (2). pp. 586-592. ISSN 0127-5720 http://msptm.org/files/Vol35No2/586-592-Suresh-K.pdf
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QH Natural history
R Medicine
spellingShingle Q Science (General)
QH Natural history
R Medicine
Farah Haziqah, Meor Termizi
Mohd Zain, Siti Nursheena
Chandrawathani, Panchacharam
Premaalatha, B.
Mohd Khalid, Mohd Khairul Nizam
Arutchelvan, R.
Govind, Suresh Kumar
Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
description Rodents are ubiquitous zoonotic vectors for many human pathogens including Blastocystis sp. In this study, we examined the prevalence and subtypes of Blastocystis sp. in rodents captured from Peninsular Malaysia. A total of 293 rodents predominantly brown rat (Rattus norvegicus) (290 of 293, 99.0%) and house shrew (Suncus murinus) (3 of 293, 1.0 %), were captured in the vicinity of popular eateries in two cities (Kuala Lumpur and Ipoh) in Peninsular Malaysia. In vitro cultivation method showed presence of Blastocystis sp. in approximately half (133 of 290, 45.9%) of the brown rats tested. Among the 47 Blastocystis isolates subtyped using partial small subunit ribosomal RNA gene analysis, ST4 was the most abundant (43 of 47, 91.5%) followed by ST1 (2 of 47, 4.3%), ST5 (1 of 47, 2.1%) and ST7 (1 of 47, 2.1%). Our findings highlighted the importance of rodents as a source of Blastocystis sp. infection in Malaysia and showed the high prevalence of ST4 within the rodent population infected with Blastocystis sp.
format Article
author Farah Haziqah, Meor Termizi
Mohd Zain, Siti Nursheena
Chandrawathani, Panchacharam
Premaalatha, B.
Mohd Khalid, Mohd Khairul Nizam
Arutchelvan, R.
Govind, Suresh Kumar
author_facet Farah Haziqah, Meor Termizi
Mohd Zain, Siti Nursheena
Chandrawathani, Panchacharam
Premaalatha, B.
Mohd Khalid, Mohd Khairul Nizam
Arutchelvan, R.
Govind, Suresh Kumar
author_sort Farah Haziqah, Meor Termizi
title Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
title_short Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
title_full Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
title_fullStr Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
title_full_unstemmed Genetic diversity of rodent blastocystis sp. From peninsular Malaysia
title_sort genetic diversity of rodent blastocystis sp. from peninsular malaysia
publisher Malaysian Society of Parasitology and Tropical Medicine
publishDate 2018
url http://eprints.um.edu.my/22092/
http://msptm.org/files/Vol35No2/586-592-Suresh-K.pdf
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score 13.211869