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Determinants of quality of life and psychological status in adults with psoriasis

We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics...

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Main Authors: Kwan, Zhenli, Bong, Yii Bonn, Tan, Leng Leng, Lim, Shu Xian, Yong, Adrian Sze Wai, Ch'ng, Chin Chwen, Tan, Maw Pin, Ismail, Rokiah
Format: Article
Published: Springer 2018
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R Medicine
Online Access:http://eprints.um.edu.my/21568/
https://doi.org/10.1007/s00403-018-1832-x
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spelling my.um.eprints.215682019-06-27T08:17:06Z http://eprints.um.edu.my/21568/ Determinants of quality of life and psychological status in adults with psoriasis Kwan, Zhenli Bong, Yii Bonn Tan, Leng Leng Lim, Shu Xian Yong, Adrian Sze Wai Ch'ng, Chin Chwen Tan, Maw Pin Ismail, Rokiah R Medicine We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics, disease severity, presence of arthropathy and head involvement was specifically recorded. Disease severity was assessed using the Psoriasis Area and Severity Index (PASI). Quality of life and psychological symptoms were measured using the Dermatology Life Quality Index (DLQI) and the Depression Anxiety Stress Scale (DASS), respectively. One hundred individuals were recruited. Unadjusted analysis revealed that head involvement was associated with depression [odds ratio (OR) 8.509; 95% confidence interval (CI) 1.077–67.231] and anxiety (OR 6.46; 95% CI 1.401–29.858). Severe disease was associated with a poorer quality of life compared to mild disease (OR 3.750; 95% CI 1.330–10.577). Younger age was associated with an increased risk of depression [mean difference (MD) − 8.640; 95% CI − 16.390 to − 0.890], anxiety (MD − 11.553; 95% CI − 18.478 to− 4.628), stress (MD − 11.440; 95% CI − 19.252 to − 3.628) and severely impaired quality of life (MD − 12.338; 95% CI − 19.548 to − 5.127). Following adjustments for age and disease severity, anxiety, stress and depression remained associated with severely impaired quality of life. Springer 2018 Article PeerReviewed Kwan, Zhenli and Bong, Yii Bonn and Tan, Leng Leng and Lim, Shu Xian and Yong, Adrian Sze Wai and Ch'ng, Chin Chwen and Tan, Maw Pin and Ismail, Rokiah (2018) Determinants of quality of life and psychological status in adults with psoriasis. Archives of Dermatological Research, 310 (5). pp. 443-451. ISSN 0340-3696 https://doi.org/10.1007/s00403-018-1832-x doi:10.1007/s00403-018-1832-x
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Kwan, Zhenli
Bong, Yii Bonn
Tan, Leng Leng
Lim, Shu Xian
Yong, Adrian Sze Wai
Ch'ng, Chin Chwen
Tan, Maw Pin
Ismail, Rokiah
Determinants of quality of life and psychological status in adults with psoriasis
description We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics, disease severity, presence of arthropathy and head involvement was specifically recorded. Disease severity was assessed using the Psoriasis Area and Severity Index (PASI). Quality of life and psychological symptoms were measured using the Dermatology Life Quality Index (DLQI) and the Depression Anxiety Stress Scale (DASS), respectively. One hundred individuals were recruited. Unadjusted analysis revealed that head involvement was associated with depression [odds ratio (OR) 8.509; 95% confidence interval (CI) 1.077–67.231] and anxiety (OR 6.46; 95% CI 1.401–29.858). Severe disease was associated with a poorer quality of life compared to mild disease (OR 3.750; 95% CI 1.330–10.577). Younger age was associated with an increased risk of depression [mean difference (MD) − 8.640; 95% CI − 16.390 to − 0.890], anxiety (MD − 11.553; 95% CI − 18.478 to− 4.628), stress (MD − 11.440; 95% CI − 19.252 to − 3.628) and severely impaired quality of life (MD − 12.338; 95% CI − 19.548 to − 5.127). Following adjustments for age and disease severity, anxiety, stress and depression remained associated with severely impaired quality of life.
format Article
author Kwan, Zhenli
Bong, Yii Bonn
Tan, Leng Leng
Lim, Shu Xian
Yong, Adrian Sze Wai
Ch'ng, Chin Chwen
Tan, Maw Pin
Ismail, Rokiah
author_facet Kwan, Zhenli
Bong, Yii Bonn
Tan, Leng Leng
Lim, Shu Xian
Yong, Adrian Sze Wai
Ch'ng, Chin Chwen
Tan, Maw Pin
Ismail, Rokiah
author_sort Kwan, Zhenli
title Determinants of quality of life and psychological status in adults with psoriasis
title_short Determinants of quality of life and psychological status in adults with psoriasis
title_full Determinants of quality of life and psychological status in adults with psoriasis
title_fullStr Determinants of quality of life and psychological status in adults with psoriasis
title_full_unstemmed Determinants of quality of life and psychological status in adults with psoriasis
title_sort determinants of quality of life and psychological status in adults with psoriasis
publisher Springer
publishDate 2018
url http://eprints.um.edu.my/21568/
https://doi.org/10.1007/s00403-018-1832-x
_version_ 1643691596817891328
score 13.211869

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