Cycloartane Triterpenoids with Anti-melanin Deposition Activity
Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down re...
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| Main Authors: | , , , , , |
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| Format: | Article |
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SAGE Publications
2018
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/21095/ https://doi.org/10.1177/1934578X1801300706 |
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| Summary: | Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down regulation of tyrosinase gene expression. |
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