Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity

The straight forwarded new green approach to the synthesis of N-phenyl benzamidine derivatives catalyzed by copper oxide nanoparticles (CuO np ) under solvent-free conditions (without microwave radiations and with MW radiation) is presented. All synthesized compounds 3a–3k are characterized by FT-IR...

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Main Authors: Taj, M.B., Tirmizi, Syed Ahmed, Raheel, Ahmad, Alelwani, W., Hajjar, D., Makki, Arwa A., Ali, U., Darroudi, Majid, Ali, Hapipah Mohd
Format: Article
Published: Pleiades Publishing 2018
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Online Access:http://eprints.um.edu.my/20572/
https://doi.org/10.1134/S1070363218110270
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spelling my.um.eprints.205722019-03-04T04:23:51Z http://eprints.um.edu.my/20572/ Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity Taj, M.B. Tirmizi, Syed Ahmed Raheel, Ahmad Alelwani, W. Hajjar, D. Makki, Arwa A. Ali, U. Darroudi, Majid Ali, Hapipah Mohd Q Science (General) QD Chemistry The straight forwarded new green approach to the synthesis of N-phenyl benzamidine derivatives catalyzed by copper oxide nanoparticles (CuO np ) under solvent-free conditions (without microwave radiations and with MW radiation) is presented. All synthesized compounds 3a–3k are characterized by FT-IR, NMR, and single crystal XRD analysis and tested for their antioxidant and elastase inhibition activities. The compounds 3i and 3j demonstrate significant free radical scavenging activity. The accumulated data indicate that some synthesized compounds can be recognized as good anti-aging agents. Pleiades Publishing 2018 Article PeerReviewed Taj, M.B. and Tirmizi, Syed Ahmed and Raheel, Ahmad and Alelwani, W. and Hajjar, D. and Makki, Arwa A. and Ali, U. and Darroudi, Majid and Ali, Hapipah Mohd (2018) Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity. Russian Journal of General Chemistry, 88 (11). pp. 2425-2431. ISSN 1070-3632 https://doi.org/10.1134/S1070363218110270 doi:10.1134/S1070363218110270
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Taj, M.B.
Tirmizi, Syed Ahmed
Raheel, Ahmad
Alelwani, W.
Hajjar, D.
Makki, Arwa A.
Ali, U.
Darroudi, Majid
Ali, Hapipah Mohd
Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
description The straight forwarded new green approach to the synthesis of N-phenyl benzamidine derivatives catalyzed by copper oxide nanoparticles (CuO np ) under solvent-free conditions (without microwave radiations and with MW radiation) is presented. All synthesized compounds 3a–3k are characterized by FT-IR, NMR, and single crystal XRD analysis and tested for their antioxidant and elastase inhibition activities. The compounds 3i and 3j demonstrate significant free radical scavenging activity. The accumulated data indicate that some synthesized compounds can be recognized as good anti-aging agents.
format Article
author Taj, M.B.
Tirmizi, Syed Ahmed
Raheel, Ahmad
Alelwani, W.
Hajjar, D.
Makki, Arwa A.
Ali, U.
Darroudi, Majid
Ali, Hapipah Mohd
author_facet Taj, M.B.
Tirmizi, Syed Ahmed
Raheel, Ahmad
Alelwani, W.
Hajjar, D.
Makki, Arwa A.
Ali, U.
Darroudi, Majid
Ali, Hapipah Mohd
author_sort Taj, M.B.
title Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
title_short Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
title_full Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
title_fullStr Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
title_full_unstemmed Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity
title_sort facile synthesis of n-phenyl benzamidine derivatives, their skin protecting, and anti-aging activity
publisher Pleiades Publishing
publishDate 2018
url http://eprints.um.edu.my/20572/
https://doi.org/10.1134/S1070363218110270
_version_ 1643691318708273152
score 13.211869