Asymmetric Total Synthesis and Biological Evaluation of Proapoptotic Natural Myrcene-Derived Cyclohexenyl Chalcones

Based on a bioinspired asymmetric Diels–Alder cycloaddition using a chiral Evans oxazolidinone, the first total synthesis of both enantiomers of two myrcene-derived cyclohexenyl chalcones, fislatifolione and fislatifolic acid, has been carried out. This strategy was also applied to the total synthes...

Full description

Saved in:
Bibliographic Details
Main Authors: Tiamas, Shelly Gapil, Audet, Florian, Samra, Alma Abou, Bignon, Jérome, Litaudon, Marc, Fourneau, Christophe, Ariffin, Azhar, Awang, Khalijah, Desrat, Sandy, Roussi, Fanny
Format: Article
Published: Wiley 2018
Subjects:
Online Access:http://eprints.um.edu.my/20469/
https://doi.org/10.1002/ejoc.201800262
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first