Development of standard clinical endpoints for use in dengue interventional trials

Dengue is a major public health problem worldwide. Although several drug candidates have been evaluated in randomized controlled trials, none has been effective and at present, early recognition of severe dengue and timely supportive care are used to reduce mortality. While the first dengue vaccine...

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Main Authors: Tomashek, Kay M., Wills, Bridget, Lum, Lucy Chai See, Thomas, Laurent, Durbin, Anna, Leo, Yee-Sin, de Bosch, Norma, Rojas, Elsa, Hendrickx, Kim, Erpicum, Martin, Agulto, Liane, Jaenisch, Thomas, Tissera, Hasitha, Suntarattiwong, Piyarat, Collers, Beth Ann, Wallace, Derek, Schmidt, Alexander C., Precioso, Alexander, Narvaez, Federico, Thomas, Stephen J., Edelman, Robert, Siqueira, João Bosco, Cassetti, M. Cristina, Dempsey, Walla, Gubler, Duane J.
Format: Article
Published: Public Library of Science 2018
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Online Access:http://eprints.um.edu.my/20459/
https://doi.org/10.1371/journal.pntd.0006497
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