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Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection

Mucosal-associated invariant T (MAIT) cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the frequency and functional role of MAIT cells in chr...

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Bibliographic Details
Main Authors: Yong, Yean K., Saeidi, Alireza, Tan, Hong Y., Rosmawati, Mohamed, Enström, Philip F., Al Batran, Rami, Vasuki, V., Chattopadhyay, Indranil, Murugesan, Amudhan, Vignesh, Ramachandran, Kamarulzaman, Adeeba, Rajarajeswaran, Jayakumar, Ansari, Abdul W., Vadivelu, Jamuna, Ussher, James E., Velu, Vijayakumar, Larsson, Marie, Shankar, Esaki Muthu
Format: Article
Published: Frontiers Media 2018
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/20260/
https://doi.org/10.3389/fimmu.2018.00472
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