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Advanced glycation end products-related modulation of cathepsin L and NF-κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα

The retinal pigment epithelium (RPE) plays a central role in neuroretinal homoeostasis throughout life. Altered proteolysis and inflammatory processes involving RPE contribute to the pathophysiology of age-related macular degeneration (AMD), but the link between these remains elusive. We report for...

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Bibliographic Details
Main Authors:	Sharif, Umar, Mahmud, Nur Musfirah, Kay, Paul, Yang, Yit C., Harding, Simon Peter, Grierson, Ian, Kamalden, Tengku Ain, Jackson, Malcolm J., Paraoan, Luminita
Format:	Article
Published:	Wiley 2018
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/19995/ https://doi.org/10.1111/jcmm.13944
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