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Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture

BACKGROUND: A comparative study between two treatment methods (collagenase injection and open partial fasciectomy) for Dupuytren's contracture. This study will determine differences in clinical outcome, complication rate and patient satisfaction. METHODS: 37 patients with 62 metacarpophalang...

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Main Authors: Tay, T.K.W., Tien, H., Lim, E.Y.L.
Format: Article
Published: World Scientific Publishing 2015
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/19580/
http://dx.doi.org/10.1142/S0218810415500288
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spelling my.um.eprints.195802018-10-03T08:41:59Z http://eprints.um.edu.my/19580/ Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture Tay, T.K.W. Tien, H. Lim, E.Y.L. R Medicine BACKGROUND: A comparative study between two treatment methods (collagenase injection and open partial fasciectomy) for Dupuytren's contracture. This study will determine differences in clinical outcome, complication rate and patient satisfaction. METHODS: 37 patients with 62 metacarpophalangeal joints (MCP) and 44 proximal interphalangeal joints (PIP) treated. There were 21 MCP joints (34%) and 8 PIP joints (18%) treated with injection. The remaining 66% of MCP joints and 82% of PIP joints were treated by open partial fasciectomy. RESULTS: Overall, both treatment methods were successful in correcting the passive extension deficit in the MCP and PIP joints. Minor complications were reported in 45% of patients in the injection group versus 42% in the surgery group. Patient satisfaction was nearly equal for both groups. CONCLUSIONS: Both treatment options have proven their effectiveness in treating Dupuytren's contracture. Open surgery is able to address additional joint contracture problems commonly associated with Dupuytren's disease. Collagenase injection has the advantage of early return of hand function and avoidance of surgical complications. World Scientific Publishing 2015 Article PeerReviewed Tay, T.K.W. and Tien, H. and Lim, E.Y.L. (2015) Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture. Hand Surgery (hs), 20 (03). pp. 386-390. ISSN 0218-8104 http://dx.doi.org/10.1142/S0218810415500288 doi:10.1142/S0218810415500288
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Tay, T.K.W.
Tien, H.
Lim, E.Y.L.
Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
description BACKGROUND: A comparative study between two treatment methods (collagenase injection and open partial fasciectomy) for Dupuytren's contracture. This study will determine differences in clinical outcome, complication rate and patient satisfaction. METHODS: 37 patients with 62 metacarpophalangeal joints (MCP) and 44 proximal interphalangeal joints (PIP) treated. There were 21 MCP joints (34%) and 8 PIP joints (18%) treated with injection. The remaining 66% of MCP joints and 82% of PIP joints were treated by open partial fasciectomy. RESULTS: Overall, both treatment methods were successful in correcting the passive extension deficit in the MCP and PIP joints. Minor complications were reported in 45% of patients in the injection group versus 42% in the surgery group. Patient satisfaction was nearly equal for both groups. CONCLUSIONS: Both treatment options have proven their effectiveness in treating Dupuytren's contracture. Open surgery is able to address additional joint contracture problems commonly associated with Dupuytren's disease. Collagenase injection has the advantage of early return of hand function and avoidance of surgical complications.
format Article
author Tay, T.K.W.
Tien, H.
Lim, E.Y.L.
author_facet Tay, T.K.W.
Tien, H.
Lim, E.Y.L.
author_sort Tay, T.K.W.
title Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
title_short Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
title_full Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
title_fullStr Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
title_full_unstemmed Comparison between Collagenase Injection and Partial Fasciectomy in the Treatment of Dupuytren’s Contracture
title_sort comparison between collagenase injection and partial fasciectomy in the treatment of dupuytren’s contracture
publisher World Scientific Publishing
publishDate 2015
url http://eprints.um.edu.my/19580/
http://dx.doi.org/10.1142/S0218810415500288
_version_ 1643691029128282112
score 13.244413

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